Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | UTS2R | Q9UKP6 | 2/20 | 0.38 |
| ▸ | ACE | P12821 | 5/20 | 0.38 |
| ▸ | PTGES | O14684 | 2/20 | 0.38 |
| ▸ | MME | P08473 | 3/20 | 0.36 |
| ▸ | CTSB | P07858 | 2/20 | 0.35 |
| ▸ | CASP1 | P29466 | 1/20 | 0.35 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.35 |
| ▸ | PPARG | P37231 | 1/20 | 0.35 |
| ▸ | PPARA | Q07869 | 1/20 | 0.35 |
| ▸ | MMP2 | P08253 | 1/20 | 0.35 |
| ▸ | MMP7 | P09237 | 1/20 | 0.35 |
| ▸ | MMP9 | P14780 | 1/20 | 0.35 |
| ▸ | MMP8 | P22894 | 1/20 | 0.35 |
| ▸ | MMP14 | P50281 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | CTSL | P07711 | 1/20 | 0.35 |
| ▸ | CTSS | P25774 | 1/20 | 0.35 |
| ▸ | LNPEP | Q9UIQ6 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8450197 | 0.90 | UTS2R (0.42) | UTS2RCTSBCASP1PPARGPPARA | |
| SCHEMBL8451272 | 0.90 | PTGES (0.39) | ACEPTGESMMECTSBLPAR1 | |
| SCHEMBL8450113 | 0.85 | MME (0.43) | UTS2RACEPTGESMMECTSB | |
| SCHEMBL8446482 | 0.82 | MME (0.49) | UTS2RACEMMECTSB | |
| SCHEMBL7573818 | 0.82 | ACE (0.56) | ACEMMECTSBLPAR1CTSL | |
| SCHEMBL7573808 | 0.82 | ACE (0.56) | ACEMMECTSBLPAR1CTSL | |
| SCHEMBL8449552 | 0.81 | ACE (0.50) | ACEPTGESMMECTSBCASP1 | |
| SCHEMBL8450247 | 0.81 | MME (0.47) | ACEMMECTSBCTSL | |
| SCHEMBL8447133 | 0.81 | MME (0.42) | UTS2RACEMMECTSB | |
| SCHEMBL8453092 | 0.81 | MME (0.43) | ACEPTGESMMECTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5968980-A | ENDOPEPTIDASE 24.11 INHIBITORS | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 1999-10-19 | — | — | US | disclosed |