SCHEMBL8450489

SCHEMBL8450489

O=Cc1cccnc1C=Cc1ccccc1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FGF23 Q9GZV9 1/20 0.48
TRIM24 O15164 1/20 0.47
TRIM33 Q9UPN9 1/20 0.47
CYP11B1 P15538 1/20 0.44
CYP11B2 P19099 1/20 0.44
MEN1 O00255 5/20 0.43
KMT2A Q03164 5/20 0.43
KDM4E B2RXH2 4/20 0.43
ALDH1A1 P00352 3/20 0.43
HPGD P15428 1/20 0.43
NPC1 O15118 4/20 0.42
RAB9A P51151 4/20 0.42
MAPT P10636 2/20 0.42
MAPK1 P28482 2/20 0.42
GLA P06280 1/20 0.42
ATM Q13315 1/20 0.42
NPSR1 Q6W5P4 1/20 0.42
L3MBTL1 Q9Y468 1/20 0.42
LMNA P02545 3/20 0.41
THRB P10828 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3397695 0.87 FGF23 (0.51) FGF23CYP11B1CYP11B2MEN1KMT2A
SCHEMBL3397697 0.87 FGF23 (0.51) FGF23CYP11B1CYP11B2MEN1KMT2A
SCHEMBL618741 0.82 FGF23 (0.48) FGF23CYP11B1CYP11B2MEN1KMT2A
Butadiene SCHEMBL7606744 0.79 FGF23 (0.46) FGF23CYP11B1CYP11B2MEN1KMT2A
SCHEMBL346904 0.78 TRIM24 (0.59) TRIM24TRIM33MEN1KMT2AKDM4E
SCHEMBL782094 0.78 FGF23 (0.44) FGF23CYP11B1CYP11B2MEN1KMT2A
SCHEMBL57902 0.76 MEN1 (0.56) CYP11B1CYP11B2MEN1KMT2AKDM4E
SCHEMBL57903 0.76 MEN1 (0.56) CYP11B1CYP11B2MEN1KMT2AKDM4E
SCHEMBL18919836 0.75 KDM4E (0.46) FGF23CYP11B1CYP11B2MEN1KMT2A
SCHEMBL6718565 0.75 KDM4E (0.43) FGF23CYP11B1CYP11B2MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-100457898-C PVA-SbQ synthesis and acetylcholinesterase fixing by same AGRO ENVIRONMENTAL PROT INST O (CN) 2009-02-04 CN claimed
CN-1766102-A PVA-SbQ synthesis and acetylcholinesterase fixing by same AGRO ENVIRONMENTAL PROT INST O (CN) 2006-05-03 CN claimed
JP-55024126-A None JP disclosed
CN-110741053-A Coating composition 株式会社ADEKA 2020-01-31 CN disclosed
CN-100457898-C PVA-SbQ synthesis and acetylcholinesterase fixing by same AGRO ENVIRONMENTAL PROT INST O (CN) 2009-02-04 CN disclosed
CN-1766102-A PVA-SbQ synthesis and acetylcholinesterase fixing by same AGRO ENVIRONMENTAL PROT INST O (CN) 2006-05-03 CN disclosed
US-5990269-A FOR USE AS A PHOTORESIST IN THE MANUFACTURE OF BLACK MATRICES AS ON COLOR CRTS BASF AKTIENGESELLSCHAFT (DE) 1999-11-23 US disclosed
US-5725978-A SUBSTITUTED DIACETONEACRYLAMIDE POLYMER, VINYLPYRROLIDONE POLYMER BASF AKTIENGESELLSCHAFT (DE) 1998-03-10 US disclosed
US-4272620-A Polyvinyl alcohol-styrylpyridinium photosensitive resins and method for manufacture thereof AGENCY OF INDUSTRIAL SCIENCE AND TECHNOLOGY (JP) 1981-06-09 US disclosed
JP-S5524126-A FORMYLSTILBAZOLIUM SALT AND ITS PREPARATION AGENCY OF IND SCIENCE & TECHNOL 1980-02-21 JP disclosed