SCHEMBL6718565

SCHEMBL6718565

C=CC=Cc1ncccc1C=Cc1ccccc1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 3/20 0.43
FGF23 Q9GZV9 1/20 0.41
NFE2L2 Q16236 3/20 0.41
TRPA1 O75762 2/20 0.41
CYP11B1 P15538 1/20 0.41
CYP11B2 P19099 1/20 0.41
MEN1 O00255 4/20 0.40
KMT2A Q03164 4/20 0.40
ALDH1A1 P00352 1/20 0.40
HPGD P15428 1/20 0.40
MAOB P27338 1/20 0.36
NPC1 O15118 3/20 0.36
RAB9A P51151 3/20 0.36
L3MBTL1 Q9Y468 2/20 0.36
ALK Q9UM73 1/20 0.36
GLA P06280 1/20 0.36
MAPT P10636 1/20 0.36
MAPK1 P28482 1/20 0.36
ATM Q13315 1/20 0.36
NPSR1 Q6W5P4 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL782094 0.94 FGF23 (0.44) KDM4EFGF23NFE2L2TRPA1CYP11B1
SCHEMBL3397697 0.86 FGF23 (0.51) KDM4EFGF23NFE2L2TRPA1CYP11B1
SCHEMBL3397695 0.86 FGF23 (0.51) KDM4EFGF23NFE2L2TRPA1CYP11B1
SCHEMBL18919836 0.85 KDM4E (0.46) KDM4EFGF23NFE2L2TRPA1CYP11B1
Butadiene SCHEMBL7606744 0.82 FGF23 (0.46) KDM4EFGF23NFE2L2TRPA1CYP11B1
SCHEMBL618741 0.81 FGF23 (0.48) KDM4EFGF23NFE2L2TRPA1CYP11B1
SCHEMBL19540178 0.81 FGF23 (0.36) KDM4EFGF23NFE2L2MEN1KMT2A
SCHEMBL1396860 0.81 FGF23 (0.36) KDM4EFGF23NFE2L2MEN1KMT2A
SCHEMBL6516708 0.78 NFE2L2 (0.33) KDM4EFGF23NFE2L2MEN1KMT2A
SCHEMBL18583178 0.78 NFE2L2 (0.33) KDM4EFGF23NFE2L2MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20040249053-A1 Adhesion promoters with epoxy-reactive groups HONEYWELL INTERNATIONAL INC. 2004-12-09 US disclosed
US-4028472-A HEAT CURABLE POLYMERIC COATING OWENS-CORNING FIBERGLAS CORPORATION (US) 1977-06-07 US disclosed
US-4014835-A GLASS FIBERS, REINFORCEMENT OWENS-CORNING FIBERGLAS CORPORATION (US) 1977-03-29 US disclosed
US-3956565-A Glass fibers coated with a silanized butadiene polymer OWENS-CORNING FIBERGLAS CORPORATION (US) 1976-05-11 US disclosed
US-3949141-A GLASS OR METAL, AZIRIDINE POLYESTERS OWENS-CORNING FIBERGLAS CORPORATION (US) 1976-04-06 US disclosed
US-3949140-A DIALKYL HYDRAZINE AND AN EPOXY SILANE OWENS-CORNING FIBERGLAS CORPORATION (US) 1976-04-06 US disclosed