SCHEMBL618741

SCHEMBL618741

C=Cc1cccnc1C=Cc1ccccc1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FGF23 Q9GZV9 1/20 0.48
CYP11B1 P15538 1/20 0.44
CYP11B2 P19099 1/20 0.44
KDM4E B2RXH2 4/20 0.43
MEN1 O00255 4/20 0.43
KMT2A Q03164 4/20 0.43
ALDH1A1 P00352 2/20 0.43
HPGD P15428 1/20 0.43
NPC1 O15118 4/20 0.42
RAB9A P51151 4/20 0.42
MAPT P10636 2/20 0.42
L3MBTL1 Q9Y468 2/20 0.42
GLA P06280 1/20 0.42
MAPK1 P28482 1/20 0.42
ATM Q13315 1/20 0.42
NPSR1 Q6W5P4 1/20 0.42
TRPA1 O75762 2/20 0.40
NFE2L2 Q16236 2/20 0.40
TSHR P16473 1/20 0.40
GRM4 Q14833 6/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Butadiene SCHEMBL7606744 0.97 FGF23 (0.46) FGF23CYP11B1CYP11B2KDM4EMEN1
SCHEMBL10901431 0.87 FGF23 (0.39) FGF23CYP11B1CYP11B2KDM4EMEN1
SCHEMBL3397697 0.87 FGF23 (0.51) FGF23CYP11B1CYP11B2KDM4EMEN1
SCHEMBL3397695 0.87 FGF23 (0.51) FGF23CYP11B1CYP11B2KDM4EMEN1
SCHEMBL18919836 0.86 KDM4E (0.46) FGF23CYP11B1CYP11B2KDM4EMEN1
SCHEMBL782094 0.85 FGF23 (0.44) FGF23CYP11B1CYP11B2KDM4EMEN1
Styrene SCHEMBL27952727 0.84 ALDH1A1 (0.52) FGF23CYP11B1CYP11B2KDM4EMEN1
SCHEMBL8450489 0.82 FGF23 (0.48) FGF23CYP11B1CYP11B2KDM4EMEN1
SCHEMBL6718565 0.81 KDM4E (0.43) FGF23CYP11B1CYP11B2KDM4EMEN1
Styrene SCHEMBL27689601 0.81 ALDH1A1 (0.48) FGF23CYP11B1CYP11B2KDM4EMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 160 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-102414362-B Adhesive composition for organic fiber cords, rubber-reinforcing material using same, tire and bonding method BRIDGESTONE CORP 2015-01-07 CN claimed
CN-101632942-B Metalloporphyrin functional poly 4-vinylpyridine-styrene composite crosslinked microsphere catalyst and preparation method thereof UNIV NORTH CHINA 2010-12-08 CN claimed
CN-101632942-A Metalloporphyrin functional poly 4-vinylpyridine-styrene composite crosslinked microsphere catalyst and preparation method thereof UNIV NORTH CHINA 2010-01-27 CN claimed
EP-1476589-A1 ACID-BASE PROTON CONDUCTING POLYMER BLEND MEMBRANE Polyfuel, Inc. (US) 2004-11-17 EP claimed
US-20030219640-A1 Acid-base proton conducting polymer blend membrane POLYFUEL, INC. (US) 2003-11-27 US claimed
WO-2003062493-A1 ACID-BASE PROTON CONDUCTING POLYMER BLEND MEMBRANE POLYFUEL, INC. (US) 2003-07-31 WO claimed
US-5296219-A Polymerizing monomer in oil in water emulsion in presence of surfactant, coating active principal with emulsion containing polymer RHONE-POULENC NUTRITION ANIMALE (FR) 1994-03-22 US claimed
US-4647615-A CURED PRODUCT OF A BIS/MALEIMIDE/ AND A 5-VINYL-2-STILBAZOLE THE UNITED STATES OF AMERICA AS REPRESENTED BY THE ADMINISTRATOR OF THE NATIONAL AERONAUTICS AND SPACE ADMINISTRATION (US) 1987-03-03 US claimed
US-4578439-A Styryl pyridine cyanates, styryl pyrazine cyanates and polymers thereof THE DOW CHEMICAL COMPANY (US) 1986-03-25 US claimed
US-4526925-A Bismaleimide copolymerized with 5-vinyl-2-stilbazole THE UNITED STATES OF AMERICA AS REPRESENTED BY THE ADMINISTRATOR OF THE NATIONAL AERONAUTICS AND SPACE ADMINISTRATION (US) 1985-07-02 US claimed
US-4471107-A Process for the prepartion of vinylpolystyrylpyridine compounds AMERICAN CYANAMID COMPANY (US) 1984-09-11 US claimed
EP-0020279-A1 Process for fractionating a polar polymer EASTMAN KODAK COMPANY (a New Jersey corporation) (US) 1980-12-10 EP claimed
US-20230270137-A1 COATED COMPOSITIONS OF BIOLOGICALLY ACTIVE INGREDIENTS FOR ORAL ADMINISTRATION TO RUMINANTS EVONIK OPERATIONS GMBH (DE) 2023-08-31 US disclosed
CN-114249905-B 3D printing polyvinyl alcohol-based hydrogel without light initiator, and preparation method and application thereof 北京化工大学 2023-06-13 CN disclosed
CN-112638255-A Electrochemical sensor comprising a plurality of working electrodes and a common reference electrode 美敦力公司 2021-04-09 CN disclosed
CN-112639469-A Electrochemical sensor comprising a plurality of working electrodes and a common reference electrode 美敦力公司 2021-04-09 CN disclosed
US-4237016-A NONIONIC SOFTENING AGENT AND A POLYMERIC CATIONIC SALT THE PROCTER & GAMBLE COMPANY (US) 1980-12-02 US disclosed
US-4205128-A FOR INDUSTRIAL USE DENKI KAGAKU KOGYO KABUSHIKI KAISHA (JP) 1980-05-27 US disclosed
US-4179382-A SOFTENERS THE PROCTER & GAMBLE COMPANY (US) 1979-12-18 US disclosed
US-3979457-A ACYLASE DENKI KAGAKU KOGYO KABUSHIKI KAISHA (JA) 1976-09-07 US disclosed