Butadiene

Butadiene

SCHEMBL7606744

C=CC=C.C=Cc1cccnc1C=Cc1ccccc1

nearest known ligand 0.46

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FGF23 Q9GZV9 1/20 0.46
CYP11B1 P15538 1/20 0.42
CYP11B2 P19099 1/20 0.42
KDM4E B2RXH2 4/20 0.41
MEN1 O00255 4/20 0.41
KMT2A Q03164 4/20 0.41
ALDH1A1 P00352 2/20 0.41
HPGD P15428 1/20 0.41
NPC1 O15118 4/20 0.40
RAB9A P51151 4/20 0.40
MAPT P10636 2/20 0.40
L3MBTL1 Q9Y468 2/20 0.40
GLA P06280 1/20 0.40
MAPK1 P28482 1/20 0.40
ATM Q13315 1/20 0.40
NPSR1 Q6W5P4 1/20 0.40
TRPA1 O75762 2/20 0.38
NFE2L2 Q16236 2/20 0.38
TSHR P16473 1/20 0.38
GRM4 Q14833 6/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL618741 0.97 FGF23 (0.48) FGF23CYP11B1CYP11B2KDM4EMEN1
SCHEMBL782094 0.85 FGF23 (0.44) FGF23CYP11B1CYP11B2KDM4EMEN1
Styrene SCHEMBL27689601 0.85 ALDH1A1 (0.48) FGF23CYP11B1CYP11B2KDM4EMEN1
SCHEMBL10901431 0.84 FGF23 (0.39) FGF23CYP11B1CYP11B2KDM4EMEN1
SCHEMBL3397697 0.84 FGF23 (0.51) FGF23CYP11B1CYP11B2KDM4EMEN1
SCHEMBL3397695 0.84 FGF23 (0.51) FGF23CYP11B1CYP11B2KDM4EMEN1
SCHEMBL18919836 0.83 KDM4E (0.46) FGF23CYP11B1CYP11B2KDM4EMEN1
SCHEMBL6718565 0.82 KDM4E (0.43) FGF23CYP11B1CYP11B2KDM4EMEN1
Styrene SCHEMBL27952727 0.81 ALDH1A1 (0.52) FGF23CYP11B1CYP11B2KDM4EMEN1
SCHEMBL8450489 0.79 FGF23 (0.48) FGF23CYP11B1CYP11B2KDM4EMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-100371378-C Industrial tire or agricultural with reinforced rubber composition GOODYEAR TIRE & RUBBER (US) 2008-02-27 CN claimed
CN-100347232-C Stabiliser combinations for polymer systems BAYER AG (DE) 2007-11-07 CN claimed
US-20150353790-A1 METHODS AND SYSTEMS FOR ADJUSTING THE COMPOSITION OF A BINDER SYSTEM CONTAINING TWO OR MORE RESINS GEORGIA-PACIFIC CHEMICALS LLC (US) 2015-12-10 US disclosed
US-9109311-B2 Two phase binder compositions and methods for making and using same GEORGIA-PACIFIC CHEMICALS LLC (US) 2015-08-18 US disclosed
EP-2844792-A1 METHODS AND SYSTEMS FOR ADJUSTING THE COMPOSITION OF A BINDER SYSTEM FOR USE IN MAKING FIBERGLASS PRODUCTS Georgia-Pacific Chemicals LLC (US) 2015-03-11 EP disclosed
CN-104271825-A Methods and systems for adjusting the composition of a binder system for use in making fiberglass products GEORGIA PACIFIC CHEMICALS LLC 2015-01-07 CN disclosed
EP-2683867-A2 TWO PHASE BINDER COMPOSITIONS AND METHODS FOR MAKING AND USING SAME Georgia-Pacific Chemicals LLC (US) 2014-01-15 EP disclosed
WO-2013166287-A1 METHODS AND SYSTEMS FOR ADJUSTING THE COMPOSITION OF A BINDER SYSTEM CONTAINING TWO OR MORE RESINS GEORGIA-PACIFIC CHEMICALS LLC (US) 2013-11-07 WO disclosed
US-20130292863-A1 METHODS AND SYSTEMS FOR ADJUSTING THE COMPOSITION OF A BINDER SYSTEM FOR USE IN MAKING FIBERGLASS PRODUCTS GEORGIA-PACIFIC CHEMICALS LLC (US) 2013-11-07 US disclosed
US-20130292864-A1 METHODS AND SYSTEMS FOR ADJUSTING THE COMPOSITION OF A BINDER SYSTEM CONTAINING TWO OR MORE RESINS GEORGIA-PACIFIC CHEMICALS LLC (US) 2013-11-07 US disclosed
WO-2013166286-A1 METHODS AND SYSTEMS FOR ADJUSTING THE COMPOSITION OF A BINDER SYSTEM FOR USE IN MAKING FIBERGLASS PRODUCTS GEORGIA-PACIFIC CHEMICALS LLC (US) 2013-11-07 WO disclosed
CN-1468904-A Heat convertible composition containing poly (arylidene ether), its producing process and products thereby ͨ�õ�����˾ 2004-01-21 CN disclosed
US-20020122938-A1 Single dip adhesive INVISTA NORTH AMERICA S.A.R.L. (F/K/A ARTEVA NORTH AMERICA S.A.R.L.) 2002-09-05 US disclosed
CN-1364184-A Curable resin compositions, methods of making, and articles made therefrom GEN ELECTRIC (US) 2002-08-14 CN disclosed
EP-1221456-A1 An adhesive comprising an epoxy compound and a resorcinol formaldehyde latex composition for coating of polyester fibres ARTEVA TECHNOLOGIES S.à.r.l. (CH) 2002-07-10 EP disclosed
CN-1076656-C Process for treating body of stainless steel so as to promote its adherence to rubber composition MICHELIN & CIE (FR) 2001-12-26 CN disclosed
CN-1140126-A Process for treating body of stainless steel so as to promote its adherence to rubber composition MICHELIN & CIE (FR) 1997-01-15 CN disclosed
US-5458544-A Applying a resorcinol-formaldehyde latex solution; drying TSUBAKIMOTO CHAIN CO. (JP) 1995-10-17 US disclosed
US-5378206-A Toothed belt having twisted core wire MITSUBOSHI BELTING LTD. (JP) 1995-01-03 US disclosed
US-4617337-A BLENDS; RHEOLOGICAL PROPERTIES EXXON RESEARCH AND ENGINEERING CO. (US) 1986-10-14 US disclosed