Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL845568 | 0.93 | RHOC (0.36) | KMT2AALDH1A1POLB | |
| SCHEMBL845565 | 0.90 | KMT2A (0.35) | KMT2AALDH1A1POLBRXFP1 | |
| SCHEMBL845438 | 0.83 | RHOC (0.41) | KMT2AALDH1A1POLB | |
| SCHEMBL845541 | 0.70 | RHOC (0.49) | KMT2AALDH1A1POLB | |
| SCHEMBL845335 | 0.64 | MAPT (0.57) | ALDH1A1POLB | |
| SCHEMBL871839 | 0.62 | PSMB8 (0.39) | — | |
| SCHEMBL13753573 | 0.61 | GAA (0.62) | KMT2AALDH1A1POLBRXFP1 | |
| SCHEMBL28282693 | 0.61 | GAA (0.62) | KMT2AALDH1A1POLBRXFP1 | |
| SCHEMBL845216 | 0.59 | NPC1 (0.46) | KMT2AALDH1A1POLB | |
| SCHEMBL845229 | 0.58 | RHOC (0.48) | KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8143288-B2 | Inhibitors of HCV replication | BRISTOL-MYERS SQUIBB COMPANY (US) | 2012-03-27 | — | — | US | disclosed |