SCHEMBL845605

SCHEMBL845605

O=C=NC(Cc1ccco1)Cc1ccco1

nearest known ligand 0.39

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 1/20 0.39
MAOB P27338 1/20 0.38
ALDH1A1 P00352 4/20 0.36
CTSS P25774 1/20 0.36
CTSK P43235 1/20 0.36
CYP3A4 P08684 1/20 0.35
ALOX15 P16050 1/20 0.35
KDM4E B2RXH2 3/20 0.35
HTT P42858 1/20 0.35
NPC1 O15118 1/20 0.35
RAB9A P51151 1/20 0.35
MAPT P10636 2/20 0.34
TSHR P16473 1/20 0.34
MEN1 O00255 1/20 0.34
KMT2A Q03164 1/20 0.34
NPSR1 Q6W5P4 1/20 0.34
USP2 O75604 1/20 0.34
L3MBTL1 Q9Y468 1/20 0.34
RIPK1 Q13546 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL109935 0.75
Furan SCHEMBL29051226 0.73 ALDH1A1 (0.40) ALOX5ALDH1A1CYP3A4ALOX15KDM4E
SCHEMBL1696704 0.72 ALOX5 (0.43) ALOX5MAOBALDH1A1CYP3A4ALOX15
SCHEMBL1696703 0.72 ALOX5 (0.43) ALOX5MAOBALDH1A1CYP3A4ALOX15
SCHEMBL1915949 0.70 MAOB (0.38) ALOX5MAOBALDH1A1CYP3A4ALOX15
SCHEMBL28805531 0.70 TXNRD1 (0.36) ALOX5ALDH1A1HTTMAPTTSHR
SCHEMBL333415 0.68 ALDH1A1 (0.46) ALOX5ALDH1A1KDM4EMAPTTSHR
SCHEMBL27176366 0.68 KMT2A (0.37) ALOX5ALDH1A1KDM4EMAPTTSHR
SCHEMBL7118218 0.67
SCHEMBL32667970 0.67

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 71 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4340807-B1 HAIR COLOR COMPOSITIONS FOR MITIGATING COLOR LOSS LUBRIZOL ADVANCED MAT INC (US) 2026-01-28 EP disclosed
EP-3233981-B1 PROCESS FOR MAKING A WATERBORNE DISPERSION COMPRISING A CATIONIC POLYAMIDE POLYMER LUBRIZOL ADVANCED MAT INC (US) 2025-07-23 EP disclosed
US-20240252419-A1 HAIR COLOR COMPOSITIONS FOR MITIGATING COLOR LOSS LUBRIZOL ADVANCED MATERIALS, INC. (US) 2024-08-01 US disclosed
US-20240208192-A1 FILM COMPRISING POLYAMIDE POLYURETHANE LAYER 3M INNOVATIVE PROPERTIES COMPANY 2024-06-27 US disclosed
US-11597838-B2 Matted polyamide-pud LUBRIZOL ADVANCED MATERIALS, INC. (US) 2023-03-07 US disclosed
EP-4132784-A1 FILM COMPRISING POLYAMIDE POLYURETHANE LAYER 3M Innovative Properties Company (US) 2023-02-15 EP disclosed
WO-2022196302-A1 READILY ADHESIVE POLYESTER FILM 東洋紡株式会社 2022-09-22 WO disclosed
US-20220259430-A1 MATTED POLYAMIDE-PUD LUBRIZOL ADVANCED MAT INC (US) 2022-08-18 US disclosed
US-20220220248-A1 SOLVENT BORNE THERMOSET POLYAMIDE URETHANE AND/OR UREA BASED COATINGS LUBRIZOL ADVANCED MATERIALS, INC. 2022-07-14 US disclosed
EP-3976682-A1 SOLVENT BORNE THERMOSET POLYAMIDE URETHANE AND/OR UREA BASED COATINGS Lubrizol Advanced Materials, Inc. (US) 2022-04-06 EP disclosed
EP-2632967-A1 FLAME-RETARDING OLIGOMERIC BROMINATED URETHANE COMPOSITIONS Lubrizol Advanced Materials, Inc. (US) 2013-09-04 EP disclosed
US-20130225755-A1 POLYMERS FOR SURGEONS GLOVES LUBRIZOL ADVANCED MATERIALS, INC. (US) 2013-08-29 US disclosed
US-20130217286-A1 FLAME-RETARDING OLIGOMERIC BROMINATED URETHANE COMPOSITIONS LUBRIZOL ADVANCED MATERIALS, INC. (US) 2013-08-22 US disclosed
US-8383713-B2 Hydrolytically stable polyurethane nanocomposites LUBRIZOL ADVANCED MATERIALS, INC. (US) 2013-02-26 US disclosed
EP-2467421-A1 HYDROLYTICALLY STABLE POLYURETHANE NANOCOMPOSITES Lubrizol Advanced Materials, Inc. (US) 2012-06-27 EP disclosed
WO-2012068059-A1 POLYMER FOR SURGEONS GLOVES LUBRIZOL ADVANCED MATERIALS, INC. (US) 2012-05-24 WO disclosed
WO-2012058534-A1 AQUEOUS CATIONIC POLYURETHANE DISPERSIONS LUBRIZOL ADVANCED MATERIALS, INC. (US) 2012-05-03 WO disclosed
WO-2012058538-A1 FLAME-RETARDING OLIGOMERIC BROMINATED URETHANE COMPOSITIONS LUBRIZOL ADVANCED MATERIALS, INC. (US) 2012-05-03 WO disclosed
WO-2011022582-A1 HYDROLYTICALLY STABLE POLYURETHANE NANOCOMPOSITES LUBRIZOL ADVANCED MATERIALS, INC. (US) 2011-02-24 WO disclosed
US-20110046286-A1 Hydrolytically Stable Polyurethane Nanocomposites LUBRIZOL ADVANCED MATERIALS, INC. (US) 2011-02-24 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240252419-A1 HAIR COLOR COMPOSITIONS FOR MITIGATING COLOR LOSS TYR, DOT1L, CUTA ALOX5 3775/4885MAOB 114/4885ALDH1A1 906/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.