Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 5/20 | 0.34 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.33 |
| ▸ | AHR | P35869 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8458190 | 0.92 | DEGS1 (0.35) | EPHX2MEN1KMT2AHIF1AEPAS1 | |
| SCHEMBL8458404 | 0.83 | HIF1A (0.38) | EPHX2MEN1KMT2AHIF1AEPAS1 | |
| SCHEMBL8459014 | 0.80 | CNR2 (0.31) | HIF1ACNR2 | |
| SCHEMBL8458293 | 0.74 | IKBKB (0.39) | MEN1KMT2AHIF1AEPAS1NPC1 | |
| SCHEMBL7926633 | 0.72 | RARB (0.43) | EPHX2MEN1KMT2AMAPTNPC1 | |
| SCHEMBL8911209 | 0.70 | RARA (0.41) | MEN1KMT2ANPC1RAB9ACNR2 | |
| SCHEMBL8458292 | 0.69 | IKBKB (0.41) | KMT2AHIF1AEPAS1CNR2 | |
| SCHEMBL8457675 | 0.69 | NPC1 (0.41) | EPHX2MEN1KMT2AHIF1AEPAS1 | |
| SCHEMBL7926531 | 0.68 | RARB (0.46) | EPHX2MEN1KMT2AMAPTTP53 | |
| SCHEMBL8616385 | 0.67 | S1PR1 (0.39) | EPHX2MEN1KMT2ACNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5952382-A | INHIBITING THE BIOLOGICAL EFFECTS OF AN OVERREGULATION OF RETINOID ACID RECEPTORS AND/OR OF A HYPERVITAMINOSIS A; TREATING SKIN DISORDER, EYE VISION DEFECTS, SKIN AGING | CENTRE INTERNATIONAL DE RECHERCHES DERMATOLOGIQUES GALDERMA (FR) | 1999-09-14 | — | — | US | disclosed |