Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IKBKB | O14920 | 4/20 | 0.41 |
| ▸ | RARA | P10276 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 4/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.34 |
| ▸ | PPARG | P37231 | 3/20 | 0.34 |
| ▸ | CNR2 | P34972 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8458293 | 0.87 | IKBKB (0.39) | IKBKBRARAHIF1AEPAS1KMT2A | |
| SCHEMBL8458404 | 0.85 | HIF1A (0.38) | IKBKBRARAHIF1AEPAS1KMT2A | |
| SCHEMBL8458442 | 0.84 | IKBKB (0.42) | IKBKBRARALMNAHIF1AEPAS1 | |
| SCHEMBL8911209 | 0.75 | RARA (0.41) | RARALMNACNR2KMT2AGPR55 | |
| SCHEMBL8909355 | 0.68 | MEN1 (0.42) | IKBKBRARAMAPK1CNR2KMT2A | |
| SCHEMBL8397777 | 0.67 | IKBKB (0.50) | IKBKBRARAMAPK1PPARG | |
| SCHEMBL8572384 | 0.67 | IKBKB (0.56) | IKBKBRARALMNAPPARGKMT2A | |
| SCHEMBL7930000 | 0.67 | IKBKB (0.51) | IKBKBRARALMNAMAPK1KMT2A | |
| SCHEMBL5888253 | 0.67 | RARA (0.62) | IKBKBRARAPPARG | |
| SCHEMBL8459014 | 0.66 | CNR2 (0.31) | HIF1ACNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5952382-A | INHIBITING THE BIOLOGICAL EFFECTS OF AN OVERREGULATION OF RETINOID ACID RECEPTORS AND/OR OF A HYPERVITAMINOSIS A; TREATING SKIN DISORDER, EYE VISION DEFECTS, SKIN AGING | CENTRE INTERNATIONAL DE RECHERCHES DERMATOLOGIQUES GALDERMA (FR) | 1999-09-14 | — | — | US | claimed |
| US-5952382-A | INHIBITING THE BIOLOGICAL EFFECTS OF AN OVERREGULATION OF RETINOID ACID RECEPTORS AND/OR OF A HYPERVITAMINOSIS A; TREATING SKIN DISORDER, EYE VISION DEFECTS, SKIN AGING | CENTRE INTERNATIONAL DE RECHERCHES DERMATOLOGIQUES GALDERMA (FR) | 1999-09-14 | — | — | US | disclosed |