Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 1/20 | 0.34 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.30 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.30 |
| ▸ | PARP1 | P09874 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8460278 | 0.91 | DRD2 (0.35) | DRD2 | |
| Hydrochloric Acid SCHEMBL8462257 | 0.86 | DRD2 (0.35) | DRD2CYP11B1CYP11B2PARP1 | |
| Hydrochloric Acid SCHEMBL4660461 | 0.86 | CHRNB2 (0.31) | — | |
| Hydrochloric Acid SCHEMBL8461606 | 0.84 | DRD2 (0.34) | DRD2CYP11B1CYP11B2PARP1 | |
| Hydrochloric Acid SCHEMBL8465321 | 0.84 | DRD2 (0.34) | DRD2CYP11B1CYP11B2PARP1 | |
| Hydrochloric Acid SCHEMBL8465872 | 0.84 | DRD2 (0.34) | DRD2CYP11B1CYP11B2PARP1 | |
| Hydrochloric Acid SCHEMBL8463874 | 0.84 | DRD2 (0.34) | DRD2CYP11B1CYP11B2PARP1 | |
| Hydrochloric Acid SCHEMBL8461390 | 0.84 | DRD2 (0.34) | DRD2CYP11B1CYP11B2PARP1 | |
| Hydrochloric Acid SCHEMBL8465442 | 0.81 | KIF11 (0.32) | DRD2 | |
| Hydrochloric Acid SCHEMBL8459038 | 0.81 | KIF11 (0.32) | DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0653433-B1 | Novel transition metal compound, olefin polymerization catalyst component comprising the transition metal compound, olefin polymerization catalyst comprising the olefin polymerization catalyst component, and process for olefin polymerization | MITSUI CHEMICALS INC (JP) | 1999-01-13 | — | — | EP | disclosed |
| EP-0653433-A1 | Novel transition metal compound, olefin polymerization catalyst component comprising the transition metal compound, olefin polymerization catalyst comprising the olefin polymerization catalyst component, and process for olefin polymerization | MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) | 1995-05-17 | — | — | EP | disclosed |