Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDH1 | O75874 | 14/20 | 0.37 |
| ▸ | AKT1 | P31749 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6747868 | 0.74 | ALDH1A1 (0.43) | IDH1RAB9ACHRM2 | |
| SCHEMBL8464221 | 0.74 | LMNA (0.33) | — | |
| SCHEMBL6747312 | 0.68 | ALDH1A1 (0.45) | IDH1AKT1RAB9ACHRM2 | |
| SCHEMBL6749181 | 0.68 | BRPF1 (0.41) | IDH1AKT1 | |
| SCHEMBL2291989 | 0.66 | GAA (0.49) | — | |
| SCHEMBL6747353 | 0.65 | ALDH1A1 (0.43) | IDH1AKT1RAB9ACHRM2 | |
| SCHEMBL6752003 | 0.64 | ALDH1A1 (0.41) | IDH1AKT1RAB9A | |
| SCHEMBL11685677 | 0.64 | TNF (0.52) | — | |
| SCHEMBL6750409 | 0.63 | AKT1 (0.35) | IDH1AKT1RAB9ACHRM2 | |
| SCHEMBL6749102 | 0.62 | ALDH1A1 (0.42) | IDH1AKT1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0934941-A1 | BENZOPIPERIDINE DERIVATIVES | Eisai Co., Ltd. (JP) | 1999-08-11 | — | — | EP | disclosed |