Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.50 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.47 |
| ▸ | ALOX5 | P09917 | 4/20 | 0.47 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.44 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.44 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.44 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.44 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.44 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8459977 | 0.78 | ALDH1A1 (0.41) | KMT2AHDAC3HDAC4HDAC1SMN1; SMN2 | |
| SCHEMBL8458616 | 0.75 | ALDH1A1 (0.40) | KMT2AMEN1HDAC3HDAC1HDAC2 | |
| SCHEMBL7452861 | 0.74 | KMT2A (0.54) | KMT2AL3MBTL1MEN1HTTKEAP1 | |
| SCHEMBL5145695 | 0.72 | KEAP1 (0.59) | KMT2AL3MBTL1MEN1HTTKEAP1 | |
| SCHEMBL448875 | 0.71 | ALOX5 (0.77) | KMT2AL3MBTL1MEN1HTTKEAP1 | |
| Phenyl Propionic Acid SCHEMBL7636781 | 0.70 | KEAP1 (0.91) | KEAP1FFAR1HDAC3MAPK1ADRA1A | |
| Phenyl Propionic Acid SCHEMBL3419 | 0.70 | KEAP1 (1.00) | KEAP1FFAR1HDAC3MAPK1ADRA1A | |
| Phenyl Propionic Acid SCHEMBL13618844 | 0.70 | KEAP1 (1.00) | KEAP1FFAR1HDAC3MAPK1ADRA1A | |
| Phenyl Propionic Acid SCHEMBL27523271 | 0.70 | KEAP1 (1.00) | KEAP1FFAR1HDAC3MAPK1ADRA1A | |
| Phenyl Propionic Acid SCHEMBL29619843 | 0.70 | KEAP1 (1.00) | KEAP1FFAR1HDAC3MAPK1ADRA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5962521-A | PROSTATE GLANDS DISORDERS | GUILFORD PHARMACEUTICALS INC. (US) | 1999-10-05 | — | — | US | disclosed |