Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | RHOC | P08134 | 1/20 | 0.46 |
| ▸ | RHOA | P61586 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.44 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.44 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.43 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL845343 | 0.95 | KMT2A (0.50) | KMT2AMEN1ALDH1A1RHOCRHOA | |
| SCHEMBL874042 | 0.86 | KMT2A (0.43) | KMT2AMEN1RHOCRHOANPSR1 | |
| SCHEMBL845290 | 0.83 | HCRTR1 (0.52) | KMT2AMEN1ALDH1A1HCRTR1HCRTR2 | |
| SCHEMBL845257 | 0.83 | TRPV1 (0.48) | KMT2AMEN1ALDH1A1RHOCRHOA | |
| SCHEMBL845629 | 0.80 | TSHR (0.50) | KMT2AMEN1ALDH1A1RHOCRHOA | |
| SCHEMBL845008 | 0.79 | ALDH1A1 (0.54) | KMT2AMEN1ALDH1A1NPSR1TSHR | |
| SCHEMBL845539 | 0.79 | HCRTR1 (0.54) | KMT2AMEN1ALDH1A1HCRTR1HCRTR2 | |
| SCHEMBL845284 | 0.78 | MAPK1 (0.58) | KMT2AMEN1ALDH1A1NPSR1GAA | |
| SCHEMBL845000 | 0.77 | RHOC (0.51) | ALDH1A1RHOCRHOATSHR | |
| SCHEMBL844996 | 0.77 | CYP2C9 (0.50) | KMT2AMEN1ALDH1A1GAATRPV1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8143288-B2 | Inhibitors of HCV replication | BRISTOL-MYERS SQUIBB COMPANY (US) | 2012-03-27 | — | — | US | disclosed |