SCHEMBL8460274

SCHEMBL8460274

N#CP(=O)(O)c1ccccc1[N+](=O)[O-]

nearest known ligand 0.45

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.45
HPGD P15428 1/20 0.45
GPR35 Q9HC97 2/20 0.41
PLAU P00749 1/20 0.41
HSD17B10 Q99714 1/20 0.40
CTSD P07339 1/20 0.40
TDP1 Q9NUW8 4/20 0.38
MEN1 O00255 1/20 0.38
KMT2A Q03164 1/20 0.38
POLB P06746 1/20 0.37
CUL4A Q13619 1/20 0.37
TSHR P16473 1/20 0.37
MAPT P10636 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31688378 0.80 ALDH1A1 (0.48) ALDH1A1GPR35PLAUHSD17B10CTSD
SCHEMBL914901 0.80 ALDH1A1 (0.48) ALDH1A1GPR35PLAUHSD17B10CTSD
SCHEMBL7775426 0.78 TSHR (0.50) ALDH1A1GPR35MEN1KMT2ATSHR
SCHEMBL7775198 0.78 TSHR (0.50) ALDH1A1HPGDGPR35HSD17B10TDP1
SCHEMBL2167182 0.77 CTSD (0.47) ALDH1A1GPR35PLAUHSD17B10CTSD
SCHEMBL10976937 0.75 HSD17B10 (0.50) ALDH1A1HPGDGPR35PLAUHSD17B10
Phosphoric Acid SCHEMBL28639142 0.75 GPR35 (0.56) ALDH1A1GPR35PLAUHSD17B10CTSD
SCHEMBL18261816 0.74 GPR35 (0.47) ALDH1A1GPR35PLAUHSD17B10CTSD
Hydrogen Sulfide SCHEMBL28247404 0.73 ALDH1A1 (0.57) ALDH1A1HPGDGPR35PLAUHSD17B10
Butane SCHEMBL3980730 0.72 HSD17B10 (0.44) ALDH1A1GPR35HSD17B10CTSDTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0948503-A1 PREPARATION OF CYANOPHOSPHONATES FROM PHOSPHATES AND CYANIDE MONSANTO COMPANY (US) 1999-10-13 EP disclosed
WO-1998029424-A1 PREPARATION OF CYANOPHOSPHONATES FROM PHOSPHATES AND CYANIDE MONSANTO COMPANY (US) 1998-07-09 WO disclosed