Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | CXCL8 | P10145 | 2/20 | 0.36 |
| ▸ | AGBL2 | Q5U5Z8 | 2/20 | 0.35 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.34 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.34 |
| ▸ | RIPK1 | Q13546 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | CES2 | O00748 | 1/20 | 0.33 |
| ▸ | CES1 | P23141 | 1/20 | 0.33 |
| ▸ | RXRA | P19793 | 1/20 | 0.33 |
| ▸ | RXRB | P28702 | 1/20 | 0.33 |
| ▸ | RXRG | P48443 | 1/20 | 0.33 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.32 |
| ▸ | ERN1 | O75460 | 1/20 | 0.32 |
| ▸ | GPR17 | Q13304 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8460359 | 0.91 | TSHR (0.40) | TSHRCXCL8AGBL2AKR1B1AKR1A1 | |
| SCHEMBL869863 | 0.77 | RIPK1 (0.47) | TSHRCXCL8AGBL2AKR1B1RIPK1 | |
| SCHEMBL29459925 | 0.77 | RIPK1 (0.47) | TSHRCXCL8AGBL2AKR1B1RIPK1 | |
| SCHEMBL8463402 | 0.76 | CXCL8 (0.34) | TSHRCXCL8AKR1B1CES2CES1 | |
| SCHEMBL20440116 | 0.74 | AGBL2 (0.39) | TSHRCXCL8AGBL2AKR1B1AKR1A1 | |
| SCHEMBL8464341 | 0.73 | POLB (0.50) | TSHRAKR1B1HSD17B10 | |
| SCHEMBL8462751 | 0.72 | CES2 (0.45) | HSD17B10CES2CES1ERN1 | |
| SCHEMBL8463501 | 0.72 | AKR1B1 (0.36) | TSHRCXCL8AKR1B1HSD17B10 | |
| SCHEMBL8464321 | 0.72 | KEAP1 (0.40) | CXCL8AKR1B1HSD17B10PTGS1 | |
| SCHEMBL8459629 | 0.72 | HPGD (0.44) | TSHRAKR1B1HSD17B10PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0745326-B1 | Stabilization of aqueous 3-isothiazolone solutions | ROHM & HAAS (US) | 1999-09-22 | — | — | EP | disclosed |
| US-5594017-A | WITH AN IODOSYL OR IODYL COMPOUND | ROHM AND HAAS COMPANY (US) | 1997-01-14 | — | — | US | disclosed |
| EP-0745326-A1 | Stabilization of aqueous 3-isothiazolone solutions | ROHM AND HAAS COMPANY (US) | 1996-12-04 | — | — | EP | disclosed |