Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 18/20 | 0.42 |
| ▸ | AKR1C2 | P52895 | 18/20 | 0.42 |
| ▸ | CA5A | P35218 | 1/20 | 0.41 |
| ▸ | AKR1B10 | O60218 | 2/20 | 0.38 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.38 |
| ▸ | AKR1C4 | P17516 | 2/20 | 0.38 |
| ▸ | AKR1C1 | Q04828 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8463268 | 0.78 | KDM4E (0.50) | — | |
| SCHEMBL8464696 | 0.76 | TPMT (0.43) | AKR1C3AKR1C2 | |
| SCHEMBL27733846 | 0.76 | KDM4E (0.47) | AKR1C3AKR1C2CA5AAKR1B10AKR1B1 | |
| SCHEMBL8460400 | 0.76 | CA1 (0.46) | — | |
| SCHEMBL8464012 | 0.74 | AKR1C3 (0.52) | AKR1C3AKR1C2CA5AAKR1C4AKR1C1 | |
| SCHEMBL8460863 | 0.74 | PTPRC (0.39) | — | |
| SCHEMBL8462420 | 0.74 | KEAP1 (0.45) | AKR1C2AKR1C1 | |
| SCHEMBL8461449 | 0.74 | AKR1C4 (0.52) | AKR1C3AKR1C2AKR1C4AKR1C1 | |
| SCHEMBL8462433 | 0.73 | SMN1; SMN2 (0.47) | AKR1C3AKR1C2CA5A | |
| SCHEMBL8462984 | 0.73 | CA12 (0.50) | CA5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0745326-B1 | Stabilization of aqueous 3-isothiazolone solutions | ROHM & HAAS (US) | 1999-09-22 | — | — | EP | disclosed |
| US-5594017-A | WITH AN IODOSYL OR IODYL COMPOUND | ROHM AND HAAS COMPANY (US) | 1997-01-14 | — | — | US | disclosed |
| EP-0745326-A1 | Stabilization of aqueous 3-isothiazolone solutions | ROHM AND HAAS COMPANY (US) | 1996-12-04 | — | — | EP | disclosed |