Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRHR1 | P34998 | 4/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16606728 | 0.77 | CRHR1 (0.59) | CRHR1 | |
| SCHEMBL5843759 | 0.74 | CRHR1 (0.56) | CRHR1 | |
| SCHEMBL5845112 | 0.73 | CRHR1 (0.55) | CRHR1 | |
| SCHEMBL242786 | 0.71 | RAPGEF4 (0.43) | CRHR1 | |
| SCHEMBL5844075 | 0.70 | CRHR1 (0.46) | CRHR1 | |
| SCHEMBL10075373 | 0.70 | APOBEC3A (0.42) | — | |
| SCHEMBL5843858 | 0.69 | CRHR1 (0.48) | CRHR1 | |
| SCHEMBL24287257 | 0.69 | SMN1; SMN2 (0.50) | CRHR1 | |
| SCHEMBL10798387 | 0.69 | RAPGEF4 (0.41) | CRHR1 | |
| Phosphine SCHEMBL22634061 | 0.69 | RAPGEF4 (0.41) | CRHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0951906-A1 | Use of 3,6-dimethyl-2-(2,4,6-trimethylphenoxy)-pyridines for treating heart failure | Pfizer Products Inc. (US) | 1999-10-27 | — | — | EP | disclosed |