Diphenylamine

Diphenylamine

SCHEMBL846236

C.c1ccc(Nc2ccccc2)cc1

nearest known ligand 0.92

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSD17B10 Q99714 5/20 0.92
ALDH1A1 P00352 8/20 0.86
TDP1 Q9NUW8 7/20 0.86
TSHR P16473 5/20 0.86
ALOX12 P18054 3/20 0.86
L3MBTL1 Q9Y468 3/20 0.86
ALOX15 P16050 2/20 0.86
PTGS1 P23219 1/20 0.86
SLC6A2 P23975 1/20 0.86
MAPK1 P28482 1/20 0.86
PTGS2 P35354 1/20 0.86
HTR2B P41595 1/20 0.86
MAPT P10636 7/20 0.71
MEN1 O00255 5/20 0.71
KMT2A Q03164 5/20 0.71
AR P10275 1/20 0.71
CYP3A4 P08684 5/20 0.63
HPGD P15428 2/20 0.63
HTT P42858 2/20 0.63
CYP1A2 P05177 2/20 0.63

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Diphenylamine SCHEMBL28099388 0.96 HSD17B10 (0.86) HSD17B10ALDH1A1TDP1TSHRALOX12
Diphenylamine SCHEMBL301493 0.96 HSD17B10 (1.00) HSD17B10ALDH1A1TDP1TSHRALOX12
Diphenylamine SCHEMBL1619083 0.96 HSD17B10 (1.00) HSD17B10ALDH1A1TDP1TSHRALOX12
Diphenylamine SCHEMBL6828443 0.96 HSD17B10 (1.00) HSD17B10ALDH1A1TDP1TSHRALOX12
Diphenylamine SCHEMBL229 0.96 HSD17B10 (1.00) HSD17B10ALDH1A1TDP1TSHRALOX12
Diphenylamine SCHEMBL3003404 0.96 HSD17B10 (1.00) HSD17B10ALDH1A1TDP1TSHRALOX12
Diphenylamine SCHEMBL23295988 0.92 HSD17B10 (0.92) HSD17B10ALDH1A1TDP1TSHRALOX12
Diphenylamine SCHEMBL634477 0.92 HSD17B10 (0.92) HSD17B10ALDH1A1TDP1TSHRALOX12
Diphenylamine SCHEMBL192934 0.92 HSD17B10 (0.92) HSD17B10ALDH1A1TDP1TSHRALOX12
Diphenylamine SCHEMBL3357779 0.92 HSD17B10 (0.92) HSD17B10ALDH1A1TDP1TSHRALOX12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 68 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109504065-A A kind of heat resist modification polyurethane rubber seal circle and preparation method thereof 五河富强鑫金属制品有限公司 2019-03-22 CN claimed
CN-107286650-A Method for producing polyimide with low dielectric constant, polyimide film and application thereof 新扬科技股份有限公司 2017-10-24 CN claimed
US-20120142938-A1 Non-halogen activating agent used as flux HUNAN ASTAR BIOTECHNOLOGY LTD (CN) 2012-06-07 US claimed
CN-101462936-A Process for producing benzophenone compound by oxidation HUASHUO TECHNOLOGY CO LTD (CN) 2009-06-24 CN claimed
CN-1929716-A Polyimide copper foil laminates and method for manufacturing same THINFLEX CORP (CN) 2007-03-14 CN claimed
CN-1284425-C Heat-resistant polyimide polymer and copper-clad circuit board thereof THINFLEX CORP (CN) 2006-11-08 CN claimed
CN-1575092-A Heat-resistant polyimide polymer and copper-clad circuit board thereof THINFLEX CORP (CN) 2005-02-02 CN claimed
CN-1202888-A Isoquinoline derivatives and isoquinoline combinatorial libraries TORREY PINES INST (US) 1998-12-23 CN claimed
US-5711927-A Method for the purification and separation of fullerenes ATWOOD JERRY L (US) 1998-01-27 US claimed
WO-1995025067-A1 METHOD FOR THE SEPARATION AND PURIFICATION OF FULLERENES ATWOOD JERRY L (US) 1995-09-21 WO claimed
US-5308885-A Polyurethane; 1,1-dichloro-2,2,2-trifluoroethane; environment MILES INC. (US) 1994-05-03 US claimed
CN-217855561-U Blender is used in methylal production 河北宇航化工有限公司 2022-11-22 CN disclosed
CN-113861664-A Wear-resistant flame-retardant TPU material and preparation method thereof 荣威达光电(东莞)有限公司 2021-12-31 CN disclosed
CN-109504065-A A kind of heat resist modification polyurethane rubber seal circle and preparation method thereof 五河富强鑫金属制品有限公司 2019-03-22 CN disclosed
CN-108728202-A Polyureas/calcium sulfonate with high base number complex grease 科聚亚(南京)化工有限公司 2018-11-02 CN disclosed
US-5272183-A HCFC blown rigid foams with low thermal conductivity MILES INC. (US) 1993-12-21 US disclosed
US-5254601-A Chlorofluorohydrocarbon as blowing agent MILES INC. (US) 1993-10-19 US disclosed
EP-0533023-A1 HCFC blown rigid foams with low thermal conductivity Bayer Corporation (US) 1993-03-24 EP disclosed
US-4943597-A Polyether polyol formulations for hard CFC replacement by water blowing in rigid polyurethane foams THE DOW CHEMICAL COMPANY (US) 1990-07-24 US disclosed
EP-0372539-A2 Polyol composition, polyisocyanate-based foams prepared therefrom and process for preparing the same THE DOW CHEMICAL COMPANY (US) 1990-06-13 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120142938-A1 Non-halogen activating agent used as flux FOS, SLC7A1, FOSB HSD17B10 4665/4885ALDH1A1 2306/4885TDP1 2445/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.