Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 11/20 | 0.47 |
| ▸ | RXRB | P28702 | 10/20 | 0.47 |
| ▸ | RXRG | P48443 | 10/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.39 |
| ▸ | RARA | P10276 | 1/20 | 0.38 |
| ▸ | RARB | P10826 | 1/20 | 0.38 |
| ▸ | MET | P08581 | 1/20 | 0.37 |
| ▸ | CFTR | P13569 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.36 |
| ▸ | CYP26B1 | Q9NR63 | 1/20 | 0.36 |
| ▸ | MGAM | O43451 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8829056 | 0.80 | RAB9A (0.42) | LMNAPOLBTSHRRAB9AHSD17B10 | |
| SCHEMBL846632 | 0.78 | DAGLA (0.42) | LMNAPOLBTSHRRAB9AHSD17B10 | |
| SCHEMBL6388617 | 0.74 | TRPV1 (0.42) | LMNAPOLBTSHRRAB9AHSD17B10 | |
| SCHEMBL845853 | 0.72 | TRPV1 (0.46) | LMNAPOLBTSHRRAB9AHSD17B10 | |
| SCHEMBL6384532 | 0.72 | TRPV1 (0.41) | LMNAPOLBTSHRRAB9AHSD17B10 | |
| SCHEMBL13616 | 0.70 | KDR (0.44) | LMNAPOLBTSHRRAB9AHSD17B10 | |
| SCHEMBL846489 | 0.69 | NPC1 (0.63) | TSHRRAB9ATRPV1RARARARB | |
| SCHEMBL846427 | 0.67 | MEN1 (0.58) | LMNAPOLBTSHRRAB9AHSD17B10 | |
| SCHEMBL860051 | 0.67 | KDM4E (0.49) | LMNAPOLBTSHRRAB9AHSD17B10 | |
| SCHEMBL8103047 | 0.67 | RXRA (0.47) | RXRARXRBRXRGRARBCYP26B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1603883-B1 | QUINOLINE-DERIVED AMIDE MODULATORS OF VANILLOID VR1 RECEPTOR | JANSSEN PHARMACEUTICA NV (BE) | 2012-03-28 | — | — | EP | claimed |