SCHEMBL8465178

SCHEMBL8465178

CC(=O)OS(c1ccccc1)(c1ccccc1)c1ccc(Cl)cc1

nearest known ligand 0.45

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 5/20 0.45
MEN1 O00255 4/20 0.45
ALOX15 P16050 1/20 0.45
TDP1 Q9NUW8 1/20 0.43
HSD11B1 P28845 2/20 0.42
FLT1 P17948 1/20 0.42
FLT4 P35916 1/20 0.42
KDR P35968 1/20 0.42
L3MBTL1 Q9Y468 1/20 0.42
LMNA P02545 2/20 0.42
PPARA Q07869 1/20 0.41
CES2 O00748 1/20 0.41
CES1 P23141 1/20 0.41
ALDH1A1 P00352 2/20 0.40
EGFR P00533 1/20 0.40
ERBB2 P04626 1/20 0.40
NPC1 O15118 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11136832 0.93 MEN1 (0.50) KMT2AMEN1ALOX15FLT1FLT4
SCHEMBL106041 0.89 BCAT1 (0.42) KMT2ATDP1HSD11B1LMNACES2
SCHEMBL699655 0.78 CES2 (0.55) KMT2AMEN1TDP1HSD11B1FLT1
SCHEMBL27880968 0.76 KMT2A (0.53) KMT2AMEN1ALOX15TDP1FLT1
Chlorobenzene SCHEMBL27828080 0.76 TSHR (0.44) KMT2AMEN1ALOX15TDP1HSD11B1
SCHEMBL1764861 0.75 LMNA (0.48) KMT2AMEN1TDP1LMNACES2
SCHEMBL11136204 0.75 ENPP2 (0.46) KMT2AMEN1LMNAALDH1A1
SCHEMBL8461136 0.72 MAPT (0.56) KMT2AMEN1TDP1LMNAALDH1A1
SCHEMBL105291 0.72 TSHR (0.44) TDP1HSD11B1LMNAALDH1A1
SCHEMBL105014 0.72 TSHR (0.44) KMT2AALOX15TDP1HSD11B1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6001932-A ACRYLIC ESTER COPOLYMER WITH VINYL ETHER, VINYL ESTER COPOLYMERS FOR RUBBER BLENDS NIPPON MEKTRON, LIMITED (JP) 1999-12-14 US disclosed
EP-0755952-B1 Acrylic copolymer elastomer, its blend rubber and blend rubber composition NIPPON MEKTRON KK (JP) 1999-10-20 EP disclosed
US-5744562-A GOOD HEAT RESISTANCE AND AMINE RESISTANCE WITH FLUORINE-CONTAINING ELASTOMER NIPPON MEKTRON, LIMITED (JP) 1998-04-28 US disclosed
EP-0755952-A2 Acrylic copolymer elastomer, its blend rubber and blend rubber composition NIPPON MEKTRON, LTD. (JP) 1997-01-29 EP disclosed
EP-0039365-B1 EPICHLOROHYDRIN ELASTOMER COMPOSITIONS MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1986-06-04 EP disclosed
US-4358559-A CURABLE TO TACK-FREE ELASTOMERIC ARTICLES MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1982-11-09 US disclosed
US-4343861-A Fluoroelastomer/polyepichlorohydrin elastomer articles MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1982-08-10 US disclosed
EP-0039365-A4 EPICHLOROHYDRIN ELASTOMER COMPOSITIONS. MINNESOTA MINING & MFG (US) 1982-03-03 EP disclosed
EP-0039365-A1 EPICHLOROHYDRIN ELASTOMER COMPOSITIONS. MINNESOTA MINING & MFG (US) 1981-11-11 EP disclosed
US-4293663-A SHAPING, CURING MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1981-10-06 US disclosed
US-4287322-A POLYPHENOL CURING AGENT MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1981-09-01 US disclosed
WO-1981001150-A1 EPICHLOROHYDRIN ELASTOMER COMPOSITIONS MINNESOTA MINING & MFG (US) 1981-04-30 WO disclosed
US-4233421-A AROMATIC POLYHYDROXY CO-CURATIVE IN A THERMALLY STABLE, CORROSION RESISTANT POLYMER MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1980-11-11 US disclosed