Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8461183 | 0.87 | — | — | |
| Hydrochloric Acid SCHEMBL8462569 | 0.86 | — | — | |
| Hydrochloric Acid SCHEMBL4659079 | 0.81 | HTR1A (0.32) | — | |
| SCHEMBL8465411 | 0.80 | — | — | |
| Hydrochloric Acid SCHEMBL8464911 | 0.80 | EDNRB (0.34) | — | |
| Hydrochloric Acid SCHEMBL8465338 | 0.78 | HTR1A (0.33) | — | |
| Hydrochloric Acid SCHEMBL6903687 | 0.77 | SLC6A4 (0.32) | — | |
| Hydrochloric Acid SCHEMBL31126400 | 0.77 | SLC6A4 (0.32) | — | |
| Hydrochloric Acid SCHEMBL8465872 | 0.77 | DRD2 (0.34) | — | |
| Hydrochloric Acid SCHEMBL4658320 | 0.77 | ALDH1A1 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5859272-A | METALLOCENES; PRODUCES POLYOLEFINS HAVING A HIGH MELTING POINT AND A HIGH MOLECULAR WEIGHT; HIGH POLYMERIZATION ACTIVITY | MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) | 1999-01-12 | — | — | US | disclosed |