Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8465429 | 0.79 | KDM4E (0.44) | KDM4ESMN1; SMN2MEN1ALDH1A1RAB9A | |
| SCHEMBL8465837 | 0.76 | LMNA (0.32) | SMN1; SMN2MEN1ALDH1A1RAB9AKMT2A | |
| SCHEMBL8463515 | 0.75 | — | — | |
| SCHEMBL8467079 | 0.74 | ALDH1A1 (0.33) | SMN1; SMN2MEN1ALDH1A1RAB9AKMT2A | |
| SCHEMBL8465617 | 0.74 | ALDH1A1 (0.33) | KDM4ESMN1; SMN2MEN1ALDH1A1RAB9A | |
| SCHEMBL8466866 | 0.70 | L3MBTL1 (0.62) | SMN1; SMN2MEN1ALDH1A1RAB9AKMT2A | |
| SCHEMBL8463544 | 0.66 | MEN1 (0.33) | SMN1; SMN2MEN1ALDH1A1RAB9AKMT2A | |
| SCHEMBL7015079 | 0.66 | — | — | |
| SCHEMBL719258 | 0.65 | RAB9A (0.41) | SMN1; SMN2MEN1ALDH1A1RAB9AKMT2A | |
| SCHEMBL8465490 | 0.64 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5952359-A | NEMATICIDES, INSECTICIDES AND MITICIDES; 1,1-DIFLUORO-3-(THIAZOLYL OR ISOTHIAZOYL-THIO (OR SULFINYL OR SULFONYL)-PROP-1-ENE DERIVATIVES | ZENECA LIMITED (GB) | 1999-09-14 | — | — | US | disclosed |
| US-5912243-A | NOVEL COMPOUNDS FOR CONTROLLING NEMATODES, INSECT OR ACARID PESTS | ZENECA LIMITED (GB) | 1999-06-15 | — | — | US | disclosed |
| US-5705516-A | NEMATOCIDES, INSECTICIDES, ACARICIDES | ZENECA LIMITED (GB) | 1998-01-06 | — | — | US | disclosed |
| EP-0749433-A1 | (4,4-DIFLUOROBUT-3-ENYLTHIO)-SUBSTITUTED HETEROCYCLIC OR CARBOCYCLIC RING COMPOUNDS HAVING PESTICIDAL ACTIVITY | ZENECA LIMITED (GB) | 1996-12-27 | — | — | EP | disclosed |
| WO-1995024403-A1 | (4,4-DIFLUOROBUT-3-ENYLTHIO)-SUBSTITUTED HETEROCYCLIC OR CARBOCYCLIC RING COMPOUNDS HAVING PESTICIDAL ACTIVITY | ZENECA LIMITED (GB) | 1995-09-14 | — | — | WO | disclosed |