Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 11/20 | 0.45 |
| ▸ | SLC6A3 | Q01959 | 8/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.40 |
| ▸ | CCR1 | P32246 | 1/20 | 0.39 |
| ▸ | MMP1 | P03956 | 1/20 | 0.39 |
| ▸ | MMP2 | P08253 | 1/20 | 0.39 |
| ▸ | MMP9 | P14780 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | DRD2 | P14416 | 1/20 | 0.36 |
| ▸ | DRD1 | P21728 | 1/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.36 |
| ▸ | ICMT | O60725 | 1/20 | 0.36 |
| ▸ | PIM1 | P11309 | 1/20 | 0.35 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22816525 | 0.82 | SLC6A4 (0.45) | SLC6A4SLC6A3SLC6A2MMP1MMP2 | |
| SCHEMBL14403245 | 0.82 | DRD2 (0.39) | SLC6A4SLC6A3DRD2HRH3 | |
| SCHEMBL20267107 | 0.80 | SLC6A4 (0.51) | SLC6A4SLC6A3SLC6A2CCR1MEN1 | |
| SCHEMBL613806 | 0.80 | POLB (0.51) | MEN1KMT2A | |
| SCHEMBL9036581 | 0.80 | OPRL1 (0.46) | SLC6A4SLC6A3SLC6A2CCR1DRD2 | |
| SCHEMBL22816524 | 0.78 | MMP1 (0.41) | SLC6A4SLC6A3SLC6A2MMP1MMP2 | |
| SCHEMBL22816520 | 0.78 | MEN1 (0.48) | SLC6A4SLC6A3SLC6A2MMP1MMP2 | |
| SCHEMBL612754 | 0.77 | OPRM1 (0.43) | SLC6A4SLC6A3SLC6A2DRD2DRD1 | |
| SCHEMBL5237277 | 0.76 | DRD2 (0.54) | SLC6A4SLC6A3SLC6A2CCR1MMP1 | |
| SCHEMBL12208869 | 0.76 | POLB (0.36) | SLC6A4SLC6A3MEN1KMT2AHRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10882856-B2 | 5 or 8-substituted imidazo [1,5-a] pyridines as selective inhibitors of indoleamine and/or tryptophane 2,3-dioxygenases | BEIGENE, LTD. (KY) | 2021-01-05 | — | — | US | disclosed |
| WO-2018054365-A1 | NOVEL 5 or 8-SUBSTITUTED IMIDAZO [1, 5-a] PYRIDINES AS SELECTIVE INHIBITORS OF INDOLEAMINE AND/OR TRYPTOPHANE 2, 3-DIOXYGENASES | BEIGENE, LTD. (KY) | 2018-03-29 | — | — | WO | disclosed |
| EP-0675187-B1 | Liquid crystalline compounds and liquid crystal composition | CHISSO CORP (JP) | 1999-09-15 | — | — | EP | disclosed |
| US-5670085-A | Liquid crystalline compound and liquid crystal | CHISSO CORPORATION (JP) | 1997-09-23 | — | — | US | disclosed |
| US-5534187-A | CONTAINING CYCLOHEXANE RING | CHISSO CORPORATION (JP) | 1996-07-09 | — | — | US | disclosed |
| EP-0675187-A2 | Liquid crystalline compounds and liquid crystal composition | Chisso Corporation (JP) | 1995-10-04 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10882856-B2 | 5 or 8-substituted imidazo [1,5-a] pyridines as selective inhibitors of indoleamine and/or tryptophane 2,3-dioxygenases | IDO1, TPH1, IDO2 | SLC6A4 159/4885SLC6A3 408/4885SLC6A2 433/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.