SCHEMBL8466283

SCHEMBL8466283

CC=CC(=O)CCC[SiH2]C(OC)OC

nearest known ligand 0.33

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
POLB P06746 1/20 0.33
POLA1 P09884 1/20 0.33
TRPA1 O75762 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL341121 0.77 ATM (0.42)
SCHEMBL21291808 0.74 HCAR2 (0.41)
SCHEMBL8461574 0.72 ATM (0.36)
SCHEMBL29059741 0.70 ALDH1A1 (0.34)
SCHEMBL2399992 0.70 POLB (0.32) POLBPOLA1
SCHEMBL704741 0.70
SCHEMBL646422 0.70
SCHEMBL1920971 0.68
SCHEMBL558284 0.68
SCHEMBL17373020 0.68

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0628605-B1 Moisture - or anaerobic-curable and photocurable silicone compositions THREE BOND CO LTD (JP) 1999-08-04 EP disclosed
US-5489622-A POLYSILOXANE, HAVING AMINO END GROUPS, REACTED WITH UNSATURATED ISOCYANATE AND MIXED WITH CURING AND PHOTOPOLYMERIZATION CATALYSTS THREE BOND CO., LTD. (JP) 1996-02-06 US disclosed
EP-0628605-A2 Moisture - or anaerobic-curable and photocurable silicone compositions THREE BOND CO., LTD. (JP) 1994-12-14 EP disclosed