Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC18A3 | Q16572 | 5/20 | 0.49 |
| ▸ | HCRTR2 | O43614 | 8/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.41 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.40 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.40 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19381000 | 1.00 | SLC18A3 (0.49) | SLC18A3HCRTR2SIGMAR1AKR1C3AKR1C1 | |
| SCHEMBL26941799 | 0.82 | DRD2 (0.49) | SLC18A3HCRTR2SIGMAR1 | |
| SCHEMBL11590148 | 0.82 | SLC18A3 (0.41) | SLC18A3HCRTR2SIGMAR1 | |
| SCHEMBL19380876 | 0.82 | SLC18A3 (0.41) | SLC18A3HCRTR2SIGMAR1 | |
| SCHEMBL12216962 | 0.81 | HRH3 (0.45) | ESR2 | |
| SCHEMBL18361625 | 0.79 | DRD2 (0.49) | SLC18A3HCRTR2SIGMAR1 | |
| SCHEMBL11619194 | 0.79 | DRD2 (0.46) | HCRTR2 | |
| SCHEMBL7080755 | 0.79 | HCRTR2 (0.39) | SLC18A3HCRTR2SIGMAR1 | |
| SCHEMBL3817201 | 0.79 | OPRM1 (0.49) | SIGMAR1 | |
| SCHEMBL3817203 | 0.79 | OPRM1 (0.49) | SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5958581-A | FORM TEREPHTHALIC ACID, ETHYLENE GLYCOL AND ISOSORBIDE MIXTURES | HNA HOLDINGS, INC. (US) | 1999-09-28 | — | — | US | claimed |
| WO-2023039218-A1 | MOISTURE ABSORBING FABRIC BLEND | MEDTEXTRA FABRIC SOLUTIONS, LLC (US) | 2023-03-16 | — | — | WO | disclosed |
| US-11008317-B2 | Triazolopyridine inhibitors of myeloperoxidase and/or EPX | BRISTOL-MYERS SQUIBB COMPANY (US) | 2021-05-18 | — | — | US | disclosed |
| US-20200291016-A1 | TRIAZOLOPYRIDINE INHIBITORS OF MYELOPEROXIDASE AND/OR EPX | BRISTOL MYERS SQUIBB CO (US) | 2020-09-17 | — | — | US | disclosed |
| WO-2017161145-A1 | TRIAZOLOPYRIDINE INHIBITORS OF MYELOPEROXIDASE AND/OR EPX | BRISTOL-MYERS SQUIBB COMPANY (US) | 2017-09-21 | — | — | WO | disclosed |
| US-5958581-A | FORM TEREPHTHALIC ACID, ETHYLENE GLYCOL AND ISOSORBIDE MIXTURES | HNA HOLDINGS, INC. (US) | 1999-09-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200291016-A1 | TRIAZOLOPYRIDINE INHIBITORS OF MYELOPEROXIDASE AND/OR EPX | EPX, MPO, SERPINB1 | SLC18A3 4123/4885HCRTR2 2550/4885SIGMAR1 3710/4885 |
| US-11008317-B2 | Triazolopyridine inhibitors of myeloperoxidase and/or EPX | EPX, MPO, SERPINB1 | SLC18A3 4123/4885HCRTR2 2550/4885SIGMAR1 3710/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.