SCHEMBL686127

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL16379414	0.86	TRPA1 (0.51)	TRPA1ALDH1A1APPTTRALOX5
	SCHEMBL2774215	0.83	TRPA1 (0.47)	TRPA1ALDH1A1TDP1TTRNFE2L2
	SCHEMBL21095690	0.82	TRPA1 (0.61)	TRPA1ALDH1A1TRIM24HPGDALDH5A1
	SCHEMBL8466367	0.82	ALDH1A1 (0.66)	TRPA1ALDH1A1TRIM24HPGDALDH5A1
	SCHEMBL901218	0.79	TRPA1 (1.00)	TRPA1ALDH1A1TRIM24HPGDALDH5A1
	SCHEMBL54199	0.79	TRPA1 (1.00)	TRPA1ALDH1A1TRIM24HPGDALDH5A1
	SCHEMBL29452839	0.79	TRPA1 (1.00)	TRPA1ALDH1A1TRIM24HPGDALDH5A1
	SCHEMBL16379413	0.79	TRPA1 (0.56)	TRPA1ALDH1A1HPGDAPPTTR
	Methyl Alcohol SCHEMBL27907460	0.78	TRPA1 (0.96)	TRPA1ALDH1A1TRIM24HPGDALDH5A1
	SCHEMBL8200354	0.78	TRPA1 (0.55)	TRPA1ALDH1A1TRIM24HPGDALDH5A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 87 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.