SCHEMBL8466396

SCHEMBL8466396

CC(c1ccccc1)(C1C=C(CCc2ccccc2)c2ccccc21)C1c2ccccc2-c2ccccc21

nearest known ligand 0.41

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
HTR6 P50406 3/20 0.41
PARK7 Q99497 1/20 0.33
MEN1 O00255 1/20 0.30
KMT2A Q03164 1/20 0.30
ATM Q13315 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8468987 0.84 HTR6 (0.34) HTR6
SCHEMBL8468905 0.82 HTR6 (0.33) HTR6
SCHEMBL8466838 0.81 HTR6 (0.32) HTR6
SCHEMBL910833 0.70 HTR6 (0.43) HTR6PARK7
SCHEMBL12815279 0.68 GPR3 (0.40) MEN1KMT2AATM
Hydrochloric Acid SCHEMBL910832 0.66 HTR6 (0.46) HTR6PARK7
SCHEMBL8158527 0.64 ACHE (0.39) HTR6
SCHEMBL6475443 0.63 HTR6 (0.38) HTR6
SCHEMBL8158524 0.63 PTPN1 (0.41) HTR6
Hydrochloric Acid SCHEMBL8160756 0.63 HTR6 (0.43) HTR6PARK7MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5886202-A HAVING UNUSUAL EFFECTIVENESS AS CATALYSTS FOR THE POLYMERIZATION OF OLEFINS WHEN CERTAIN SUBSTITUENTS ARE AT THE 3 POSITION OF THE INDENE; HIGHER-MOLECULAR-WEIGHT POLYOLEFINS CHEVRON PHILLIPS CHEMICAL COMPANY LP 1999-03-23 US disclosed