Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 13/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL846662 | 0.84 | TRPV1 (0.62) | TRPV1RAB9A | |
| SCHEMBL846954 | 0.78 | TRPV1 (0.45) | TRPV1LMNAPOLBTSHRRAB9A | |
| SCHEMBL847040 | 0.77 | TRPV1 (0.61) | TRPV1RAB9A | |
| SCHEMBL846419 | 0.77 | ACHE (0.47) | TRPV1RAB9AHSD17B10 | |
| SCHEMBL848239 | 0.75 | RAB9A (0.47) | TRPV1LMNAPOLBTSHRRAB9A | |
| SCHEMBL846206 | 0.74 | MEN1 (0.55) | TRPV1LMNAPOLBTSHRRAB9A | |
| SCHEMBL4108874 | 0.73 | KDR (0.63) | TRPV1LMNAPOLBTSHRRAB9A | |
| SCHEMBL846566 | 0.73 | HSD17B10 (0.44) | TRPV1LMNAPOLBTSHRRAB9A | |
| SCHEMBL846454 | 0.71 | TRPV1 (0.57) | TRPV1LMNAPOLBTSHRRAB9A | |
| SCHEMBL6255052 | 0.71 | MTNR1A (0.52) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1603883-B1 | QUINOLINE-DERIVED AMIDE MODULATORS OF VANILLOID VR1 RECEPTOR | JANSSEN PHARMACEUTICA NV (BE) | 2012-03-28 | — | — | EP | claimed |