Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKT1 | P31749 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | CES2 | O00748 | 2/20 | 0.35 |
| ▸ | CES1 | P23141 | 2/20 | 0.35 |
| ▸ | DAO | P14920 | 1/20 | 0.35 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | MAOA | P21397 | 4/20 | 0.34 |
| ▸ | MAOB | P27338 | 4/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | XBP1 | P17861 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11720470 | 0.77 | AKT1 (0.40) | AKT1ALDH1A1TSHRCES2CES1 | |
| SCHEMBL146099 | 0.75 | CES1 (0.43) | AKT1ALDH1A1TSHRCES2CES1 | |
| SCHEMBL8377031 | 0.74 | CES2 (0.47) | CES2CES1MAOB | |
| SCHEMBL9119892 | 0.74 | MAPT (0.42) | AKT1ALDH1A1TSHRCES2CES1 | |
| SCHEMBL1498036 | 0.70 | MAOA (0.44) | AKT1ALDH1A1TSHRCES2CES1 | |
| SCHEMBL6865935 | 0.70 | MAOA (0.41) | AKT1ALDH1A1TSHRCES2CES1 | |
| SCHEMBL330617 | 0.70 | ALDH1A1 (0.42) | AKT1ALDH1A1TSHRCES2CES1 | |
| Methane SCHEMBL10894930 | 0.68 | ALDH1A1 (0.41) | ALDH1A1TSHRCES2CES1DAO | |
| SCHEMBL8210944 | 0.68 | MEN1 (0.58) | AKT1ALDH1A1TSHRCES2CES1 | |
| SCHEMBL108144 | 0.67 | AKT1 (0.54) | AKT1ALDH1A1TSHRCES2CES1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5925670-A | AVERMECTIN INSECTICIDE FOR COCKROACHES WITH FRUCTOSE | THE CLOROX COMPANY (US) | 1999-07-20 | — | — | US | disclosed |