SCHEMBL8467928

SCHEMBL8467928

S=C(Cl)OCc1ccccc1

nearest known ligand 0.63

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.63
CA12 O43570 1/20 0.61
CA1 P00915 1/20 0.61
CA2 P00918 1/20 0.61
CA9 Q16790 1/20 0.61
TDP1 Q9NUW8 2/20 0.50
SLC6A2 P23975 2/20 0.50
SLC6A3 Q01959 2/20 0.50
MAPK1 P28482 1/20 0.50
L3MBTL1 Q9Y468 1/20 0.50
KMT2A Q03164 1/20 0.50
TSHR P16473 2/20 0.48
LMNA P02545 4/20 0.46
HCAR2 Q8TDS4 1/20 0.46
IDO1 P14902 1/20 0.44
AGXT P21549 1/20 0.43
MMP2 P08253 1/20 0.42
MMP9 P14780 1/20 0.42
MMP12 P39900 1/20 0.42
CYP1A2 P05177 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28218969 0.81 CA12 (0.65) ALDH1A1CA12CA1CA2CA9
SCHEMBL1722105 0.81 CA12 (0.65) ALDH1A1CA12CA1CA2CA9
SCHEMBL7055323 0.81 ALDH1A1 (0.68) ALDH1A1CA12CA1CA2CA9
SCHEMBL11231967 0.80 IDO1 (0.50) ALDH1A1CA12CA1CA2CA9
Hydrochloric Acid SCHEMBL11753023 0.79 CA12 (0.63) ALDH1A1CA12CA1CA2CA9
SCHEMBL11686215 0.78 HCAR2 (0.49) ALDH1A1CA12CA1CA2CA9
SCHEMBL7049526 0.77 ALDH1A1 (0.63) ALDH1A1CA12CA1CA2CA9
SCHEMBL13189381 0.77 ALDH1A1 (0.63) ALDH1A1CA12CA1CA2CA9
SCHEMBL10767903 0.77 CA12 (0.61) ALDH1A1CA12CA1CA2CA9
SCHEMBL960 0.77 ALDH1A1 (1.00) ALDH1A1CA12CA1CA2CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11845726-B2 C4-carbonothioate-substituted tryptamine derivatives and methods of using Enveric Biosciences Canada Inc. (CA) 2023-12-19 US claimed
CN-107532229-B Process for leaching metal sulphides with an agent having a thiocarbonyl function 不列颠哥伦比亚大学 2021-10-08 CN claimed
JP-59122459-A None JP disclosed
JP-59144752-A None JP disclosed
US-20250352513-A2 SALTS OF C4-CARBOXYLIC ACID- AND C4-CARBONOTHIOATE-SUBSTITUTED TRYPTAMINE DERIVATIVES AND METHODS OF USING ENVERIC BIOSCIENCES CANADA INC (CA) 2025-11-20 US disclosed
US-20250205197-A1 SALTS OF C4-CARBOXYLIC ACID- AND C4-CARBONOTHIOATE-SUBSTITUTED TRYPTAMINE DERIVATIVES AND METHODS OF USING Enveric Biosciences Canada Inc. (CA) 2025-06-26 US disclosed
US-20250206701-A1 C4-CARBONOTHIOATE-SUBSTITUTED TRYPTAMINE DERIVATIVES AND METHODS OF USING Enveric Biosciences Canada Inc. (CA) 2025-06-26 US disclosed
EP-4493542-A1 C4-CARBONOTHIOATE-SUBSTITUTED TRYPTAMINE DERIVATIVES AND METHODS OF USING Enveric Biosciences Canada Inc. (CA) 2025-01-22 EP disclosed
EP-4493544-A1 SALTS OF C4-CARBOXYLIC ACID- AND C4-CARBONOTHIOATE-SUBSTITUTED TRYPTAMINE DERIVATIVES AND METHODS OF USING Enveric Biosciences Canada Inc. (CA) 2025-01-22 EP disclosed
US-11945778-B2 C4-carbonothioate-substituted tryptamine derivatives and methods of using Enveric Biosciences Canada Inc. (CA) 2024-04-02 US disclosed
US-11845726-B2 C4-carbonothioate-substituted tryptamine derivatives and methods of using Enveric Biosciences Canada Inc. (CA) 2023-12-19 US disclosed
US-20150359786-A1 ANTIVIRAL COMPOUNDS AND METHODS OF USE THEREOF TRANA DISCOVERY, INC. 2015-12-17 US disclosed
US-5962487-A PICORNAVIRAL 3C PROTEASE INHIBITORS AGOURON PHARMACEUTICALS, INC. (US) 1999-10-05 US disclosed
US-5171356-A Thiolcarbamate and nonphytotoxic extender which minimizes soil degradation ICI AMERICAS INC. (US) 1992-12-15 US disclosed
EP-0175332-B1 HERBICIDE COMPOSITIONS OF EXTENDED SOIL LIFE STAUFFER CHEMICAL COMPANY (US) 1992-03-18 EP disclosed
US-4740623-A BENZYL CHLORIDE REACTED WITH SODIUM HYDROSULFIDE STAUFFER CHEMICAL COMPANY (US) 1988-04-26 US disclosed
JP-S59144752-A BENZYLTHIOLCARBAMATE DERIVATIVE, ITS PREPARATION AND HERBICIDE CONTAINING SAID DERIVATIVE AS ACTIVE COMPONENT SUMITOMO CHEM CO LTD 1984-08-18 JP disclosed
JP-S59122459-A BENZAMIDINE COMPOUND AND AGRICULTURAL AND HORTICULTURAL FUNGICIDE UBE IND LTD 1984-07-14 JP disclosed
US-4097457-A Process for preparing high molecular weight polycarbonates MITSUBISHI GAS CHEMICAL COMPANY, INC. (JA) 1978-06-27 US disclosed
US-4040812-A Herbicidal carbonates and thiocarbonates of thiadiazolyl-2(1H)-pyrimidinones VELSICOL CHEMICAL CORPORATION (US) 1977-08-09 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11845726-B2 C4-carbonothioate-substituted tryptamine derivatives and methods of using HTR4, SLC6A4, HTR6 ALDH1A1 1613/4885CA12 2326/4885CA1 2401/4885
US-11945778-B2 C4-carbonothioate-substituted tryptamine derivatives and methods of using HTR4, SLC6A4, HTR6 ALDH1A1 1613/4885CA12 2326/4885CA1 2401/4885
US-20150359786-A1 ANTIVIRAL COMPOUNDS AND METHODS OF USE THEREOF TYMP, MAVS, ZC3HAV1 ALDH1A1 2506/4885CA12 4728/4885CA1 4655/4885
US-20250205197-A1 SALTS OF C4-CARBOXYLIC ACID- AND C4-CARBONOTHIOATE-SUBSTITUTED TRYPTAMINE DERIVATIVES AND METHODS OF USING SLC6A4, HTR2B, SLC6A3 ALDH1A1 1171/4885CA12 699/4885CA1 542/4885
US-20250352513-A2 SALTS OF C4-CARBOXYLIC ACID- AND C4-CARBONOTHIOATE-SUBSTITUTED TRYPTAMINE DERIVATIVES AND METHODS OF USING SLC6A4, HTR4, SLC6A3 ALDH1A1 1131/4885CA12 723/4885CA1 567/4885
US-20250206701-A1 C4-CARBONOTHIOATE-SUBSTITUTED TRYPTAMINE DERIVATIVES AND METHODS OF USING HTR4, SLC6A4, HTR6 ALDH1A1 1613/4885CA12 2326/4885CA1 2401/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.