Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 5/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 5/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.45 |
| ▸ | HPGD | P15428 | 3/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 3/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | RPS6KA2 | Q15349 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8467804 | 0.81 | HSP90AA1 (0.58) | LMNAMAPTMAPK1MEN1KMT2A | |
| SCHEMBL8467109 | 0.80 | HSP90AA1 (0.60) | LMNAMAPTMAPK1MEN1KMT2A | |
| SCHEMBL4391609 | 0.76 | MGLL (0.49) | LMNAMEN1KMT2AALDH1A1HPGD | |
| SCHEMBL94147 | 0.75 | MGLL (0.46) | MAPK1MEN1KMT2ATDP1 | |
| SCHEMBL15347091 | 0.74 | RAB9A (0.55) | LMNAMAPTMEN1KMT2AL3MBTL1 | |
| SCHEMBL8995936 | 0.74 | MEN1 (0.55) | LMNAMAPTMAPK1MEN1KMT2A | |
| SCHEMBL9514574 | 0.73 | NQO1 (0.70) | LMNAMAPTMAPK1MEN1KMT2A | |
| SCHEMBL49554 | 0.73 | NQO1 (0.70) | LMNAMAPTMAPK1MEN1KMT2A | |
| SCHEMBL1471713 | 0.73 | LMNA (0.49) | LMNAMAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL23701392 | 0.73 | LMNA (0.64) | LMNAMAPTMEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5936038-A | MIXTURE CONTAINING ELASTOMER HAVING PENDANT REACTIVE AMINE GROUP AND PHENOLIC RESIN CURATIVE | THE UNIVERSITY OF AKRON (US) | 1999-08-10 | — | — | US | claimed |
| US-5936038-A | MIXTURE CONTAINING ELASTOMER HAVING PENDANT REACTIVE AMINE GROUP AND PHENOLIC RESIN CURATIVE | THE UNIVERSITY OF AKRON (US) | 1999-08-10 | — | — | US | disclosed |
| EP-0570825-B1 | Tire sidewall composition containing silica having low PH | GOODYEAR TIRE & RUBBER (US) | 1996-08-07 | — | — | EP | disclosed |
| EP-0475215-B1 | Carboxylic acid esters with thio groups | GOODYEAR TIRE & RUBBER (US) | 1994-10-19 | — | — | EP | disclosed |
| EP-0570825-A1 | Tire sidewall composition containing silica having low PH | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1993-11-24 | — | — | EP | disclosed |
| US-5244028-A | Natural rubber or polybutadiene, silica, antidegradation agent, carbon black | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1993-09-14 | — | — | US | disclosed |
| US-5216049-A | A phenolic or amine stabilizer and an organothioalkylene styrene bound to a polymer; aging resistance; rubbers | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1993-06-01 | — | — | US | disclosed |
| EP-0475215-A1 | Carboxylic acid esters with thio groups | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1992-03-18 | — | — | EP | disclosed |
| US-5069819-A | SYNERGISTS FOR CONVENTIONAL PHENOLIC AND AMINE ANTIOXIDANTS | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1991-12-03 | — | — | US | disclosed |