SCHEMBL8468282

SCHEMBL8468282

CC1=C(C)C(C)(C)C(Cc2ccccc2)=C1C

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CALM1 P0DP23 1/20 0.42
ELANE P08246 1/20 0.36
ANPEP P15144 1/20 0.36
LAP3 P28838 1/20 0.36
TAAR1 Q96RJ0 5/20 0.35
SIGMAR1 Q99720 2/20 0.35
SLC18A2 Q05940 1/20 0.35
LTA4H P09960 1/20 0.35
TP53 P04637 1/20 0.34
KDM4E B2RXH2 1/20 0.34
CYP3A4 P08684 1/20 0.34
MAPT P10636 1/20 0.34
IDH1 O75874 1/20 0.34
SLC6A2 P23975 2/20 0.33
MAOA P21397 1/20 0.33
SLC6A4 P31645 1/20 0.33
SLC6A3 Q01959 1/20 0.33
LMNA P02545 1/20 0.33
NPC1 O15118 1/20 0.33
HPGD P15428 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Biphenyl SCHEMBL9166896 0.82 ALDH1A1 (0.35) TAAR1CYP3A4SLC6A2SLC6A4SLC6A3
SCHEMBL8463234 0.81 CALM1 (0.39) CALM1ELANEANPEPLAP3TAAR1
SCHEMBL21084790 0.68 ELANE (0.48) CALM1ELANETP53MAOA
SCHEMBL4871056 0.68 CYP1A2 (0.36) ELANETAAR1KDM4EMAOAHPGD
SCHEMBL4425491 0.68 ELANE (0.33) ELANETP53
SCHEMBL3027831 0.68 ELANE (0.33) ELANEANPEPLAP3TP53
SCHEMBL8846638 0.68 ELANE (0.33) ELANETP53
SCHEMBL7754774 0.68 ELANE (0.33) ELANETP53
SCHEMBL7171055 0.68 ELANE (0.33) ELANETAAR1TP53KDM4ECYP3A4
SCHEMBL21044913 0.68 TP53 (0.34) CALM1ELANETAAR1TP53KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10752992-B2 Atomic layer deposition method of metal-containing thin film KOJUNDO CHEMICAL LABORATORY CO., LTD. (JP) 2020-08-25 US disclosed
US-20190203357-A1 ATOMIC LAYER DEPOSITION METHOD OF METAL-CONTAINING THIN FILM KOJUNDO CHEMICAL LABORATORY CO., LTD. (JP) 2019-07-04 US disclosed
US-5986029-A POLYMERIZATION CATALYSTS FOR OLEFINS USING TRANSITION METAL COMPLEXES AND COCATALYST DSM N.V. (NL) 1999-11-16 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10752992-B2 Atomic layer deposition method of metal-containing thin film ADH1A, ADH5, ADH1C CALM1 3335/4885ELANE 3610/4885ANPEP 4709/4885
US-20190203357-A1 ATOMIC LAYER DEPOSITION METHOD OF METAL-CONTAINING THIN FILM ADH1A, ADH5, ADH1C CALM1 3335/4885ELANE 3610/4885ANPEP 4709/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.