Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EBP | Q15125 | 1/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.41 |
| ▸ | ESR1 | P03372 | 7/20 | 0.38 |
| ▸ | MPO | P05164 | 1/20 | 0.36 |
| ▸ | CYP27A1 | Q02318 | 3/20 | 0.35 |
| ▸ | CYP24A1 | Q07973 | 3/20 | 0.35 |
| ▸ | CYP26A1 | O43174 | 1/20 | 0.34 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | ALKBH3 | Q96Q83 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8466618 | 0.85 | SIGMAR1 (0.58) | EBPSIGMAR1ESR1CYP27A1CYP24A1 | |
| SCHEMBL8466830 | 0.83 | MPO (0.46) | EBPSIGMAR1MPOCYP27A1CYP24A1 | |
| SCHEMBL8468620 | 0.78 | EBP (0.41) | EBPSIGMAR1ESR1MPOCYP27A1 | |
| SCHEMBL7624883 | 0.73 | ESR1 (0.60) | EBPSIGMAR1ESR1CYP27A1CYP24A1 | |
| SCHEMBL113833 | 0.73 | EBP (0.73) | EBPSIGMAR1ESR1 | |
| SCHEMBL115122 | 0.72 | EBP (0.47) | EBPSIGMAR1ESR1MPOCYP27A1 | |
| SCHEMBL26957546 | 0.72 | ESR1 (0.42) | EBPSIGMAR1ESR1ALDH1A1ALKBH3 | |
| SCHEMBL7633352 | 0.70 | MIF (0.48) | ESR1CYP27A1CYP26A1ALDH1A1ALKBH3 | |
| SCHEMBL23297257 | 0.69 | EBP (0.51) | EBPSIGMAR1ESR1CYP27A1CYP26A1 | |
| SCHEMBL27320516 | 0.69 | TLR9 (0.42) | EBPSIGMAR1ESR1CYP27A1CYP26A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5948809-A | (-) cis-6(S)-phenyl-5(R) 4-(2-pyrrolidin-1-yl ethoxy) phenyl!-5,6,7,8-tetrahydronaphthalen-2-ol-D-tartrate | PFIZER INC (US) | 1999-09-07 | — | — | US | disclosed |