Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 3/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | ESR1 | P03372 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | RECQL | P46063 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.39 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.39 |
| ▸ | GMNN | O75496 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19404310 | 1.00 | ALOX15 (0.39) | ALOX15ALOX12ALDH1A1KDM4EMEN1 | |
| SCHEMBL2623873 | 0.83 | GABRA1 (0.48) | ALOX15ALOX12ALDH1A1KDM4EMEN1 | |
| SCHEMBL9176216 | 0.83 | GABRA1 (0.48) | ALOX15ALOX12ALDH1A1KDM4EMEN1 | |
| SCHEMBL22122818 | 0.82 | PNMT (0.46) | ALOX15ALOX12ALDH1A1KDM4EMEN1 | |
| SCHEMBL22122819 | 0.82 | PNMT (0.46) | ALOX15ALOX12ALDH1A1KDM4EMEN1 | |
| SCHEMBL22145308 | 0.82 | PNMT (0.46) | ALOX15ALOX12ALDH1A1KDM4EMEN1 | |
| SCHEMBL28747785 | 0.82 | PNMT (0.46) | KDM4EMEN1CYP3A4KMT2ALMNA | |
| SCHEMBL14402555 | 0.82 | RIPK1 (0.41) | ALDH1A1CYP3A4DPP4MAOAMAOB | |
| SCHEMBL27835674 | 0.80 | FOS (0.51) | ALOX15ALOX12CYP3A4NR3C1FOS | |
| SCHEMBL27853740 | 0.80 | FOS (0.51) | ALOX15ALOX12CYP3A4NR3C1FOS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999048530-A1 | COMBINATION THERAPY FOR THE TREATMENT OF BENIGN PROSTATIC HYPERPLASIA | MERCK & CO., INC. (US) | 1999-09-30 | — | — | WO | disclosed |