Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20378032 | 0.86 | ALDH1A1 (0.33) | LMNAHTTCYP3A4HSD11B1MEN1 | |
| SCHEMBL9223000 | 0.82 | SLC18A3 (0.38) | LMNAHSD11B1TDP1MAPTKMT2A | |
| SCHEMBL9142790 | 0.81 | HSD11B1 (0.35) | AKR1C1LMNAHTTHSD11B1THRB | |
| Hydrochloric Acid SCHEMBL28568646 | 0.81 | HSD11B1 (0.35) | AKR1C1LMNAHTTHSD11B1THRB | |
| SCHEMBL9253524 | 0.80 | THRB (0.36) | AKR1C1THRBTDP1MEN1KMT2A | |
| SCHEMBL17707789 | 0.79 | AKR1C1 (0.33) | AKR1C1LMNAHTTHSD11B1THRB | |
| SCHEMBL27621152 | 0.78 | LMNA (0.33) | AKR1C1LMNAHTTCYP3A4HSD11B1 | |
| SCHEMBL3262268 | 0.77 | AKR1C1 (0.32) | AKR1C1LMNAHTTSMN1; SMN2 | |
| SCHEMBL7546042 | 0.76 | P2RX1 (0.32) | AKR1C1 | |
| SCHEMBL29963909 | 0.73 | HSD11B1 (0.33) | HSD11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5942365-A | CHARGE ADJUVANT OF ALUMINUM SALT OF AN ACID; SMEARING, LOSS OF RESOLUTION AND LOSS OF DENSITY ELIMINATED OR MINIMIZED | XEROX CORPORATION (US) | 1999-08-24 | — | — | US | claimed |
| US-5942365-A | CHARGE ADJUVANT OF ALUMINUM SALT OF AN ACID; SMEARING, LOSS OF RESOLUTION AND LOSS OF DENSITY ELIMINATED OR MINIMIZED | XEROX CORPORATION (US) | 1999-08-24 | — | — | US | disclosed |
| US-5672457-A | MELT MIXING THERMOPLASTIC RESINS WITH CHARGING AGENTS | XEROX CORPORATION (US) | 1997-09-30 | — | — | US | disclosed |