Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | F2 | P00734 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 3/20 | 0.38 |
| ▸ | CES2 | O00748 | 2/20 | 0.38 |
| ▸ | CES1 | P23141 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | DAO | P14920 | 1/20 | 0.38 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.38 |
| ▸ | MAOA | P21397 | 2/20 | 0.37 |
| ▸ | MAOB | P27338 | 2/20 | 0.37 |
| ▸ | AKT1 | P31749 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | XBP1 | P17861 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | F10 | P00742 | 1/20 | 0.35 |
| ▸ | F12 | P00748 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL214249 | 0.78 | LMNA (0.42) | LMNAF2TSHRCES2CES1 | |
| SCHEMBL13242263 | 0.76 | TSHR (0.42) | LMNAF2TSHRCES2CES1 | |
| Methane SCHEMBL756715 | 0.76 | LMNA (0.40) | LMNAF2TSHRCES2CES1 | |
| SCHEMBL16486462 | 0.74 | CES2 (0.42) | LMNAF2TSHRCES2CES1 | |
| SCHEMBL22593580 | 0.74 | MAOA (0.41) | LMNAF2TSHRCES2CES1 | |
| SCHEMBL269069 | 0.74 | TSHR (0.52) | LMNAF2TSHRCES2CES1 | |
| SCHEMBL5835648 | 0.74 | LMNA (0.44) | LMNAF2TSHRCES2CES1 | |
| SCHEMBL4206079 | 0.72 | ELANE (0.48) | LMNAF2TSHRALDH1A1MAPT | |
| SCHEMBL3194850 | 0.72 | LMNA (0.37) | LMNAF2TSHRCES2CES1 | |
| SCHEMBL3205106 | 0.72 | LMNA (0.37) | LMNAF2TSHRCES2CES1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110483364-B | Indolone sulfone compound and synthesis method thereof | 台州学院 | 2020-12-25 | — | — | CN | claimed |
| CN-105793326-B | Moisture-curable compositions with metal-arene complexes | 莫门蒂夫性能材料股份有限公司 | 2020-07-21 | — | — | CN | claimed |
| US-20170174840-A1 | MOISTURE CURABLE SILICONE COMPOSITION | MOMENTIVE PERFORMANCE MATERIALS INC. | 2017-06-22 | — | — | US | claimed |
| JP-11228535-A | — | — | None | — | — | JP | disclosed |
| CN-117916323-A | Non-sagging composition | 迈图高新材料公司 | 2024-04-19 | — | — | CN | disclosed |
| CN-116888194-A | Condensation curable composition comprising a siloxane-imide base polymer | 迈图高新材料公司 | 2023-10-13 | — | — | CN | disclosed |
| CN-113260677-A | Electrostatic dissipative room temperature vulcanizable silicones | 迈图高新材料公司 | 2021-08-13 | — | — | CN | disclosed |
| CN-107109063-B | Thermoplastic composition comprising polyamide and polysiloxane | 汉高股份有限及两合公司 | 2021-02-19 | — | — | CN | disclosed |
| US-10738006-B2 | Method for oxygenative coupling of alkynes using acid catalyst | INDUSTRY-UNIVERSITY COOPERATION FOUNDATION HANYANG UNIVERSITY (KR) | 2020-08-11 | — | — | US | disclosed |
| CN-105793326-B | Moisture-curable compositions with metal-arene complexes | 莫门蒂夫性能材料股份有限公司 | 2020-07-21 | — | — | CN | disclosed |
| US-20180282273-A1 | METHOD FOR OXYGENATIVE COUPLING OF ALKYNES USING ACID CATALYST | INDUSTRY-UNIVERSITY COOPERATION FOUNDATION HANYANG UNIVERSITY (KR) | 2018-10-04 | — | — | US | disclosed |
| JP-H11228535-A | NEW COMPOUND AND ANTI-DERMATITIS AGENT | TSUMURA & CO | 1999-08-24 | — | — | JP | disclosed |
| US-5328958-A | Thermoplastic resins based on vinyl aromatic/vinyl phosphonic acid copolymers and amine-terminated polymers | ARCO CHEMICAL TECHNOLOGY, L.P. (US) | 1994-07-12 | — | — | US | disclosed |
| WO-1983000156-A1 | ONE PACKAGE, STABLE, MOISTURE CURABLE, POLYALKOXY-TERMINATED ORGANOPOLYSILOXANE COMPOSITIONS AND METHOD FOR MAKING | GEN ELECTRIC (US) | 1983-01-20 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10738006-B2 | Method for oxygenative coupling of alkynes using acid catalyst | SQOR, CYBB, AOX1 | LMNA 3793/4885F2 1410/4885TSHR 3599/4885 |
| US-20180282273-A1 | METHOD FOR OXYGENATIVE COUPLING OF ALKYNES USING ACID CATALYST | SQOR, CYBB, AOX1 | LMNA 3793/4885F2 1410/4885TSHR 3599/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.