Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
| ▸ | MAOA | P21397 | 3/20 | 0.40 |
| ▸ | MAOB | P27338 | 3/20 | 0.40 |
| ▸ | RIPK2 | O43353 | 2/20 | 0.39 |
| ▸ | KDR | P35968 | 2/20 | 0.39 |
| ▸ | EGFR | P00533 | 1/20 | 0.39 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.39 |
| ▸ | RIPK3 | Q9Y572 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.37 |
| ▸ | NAMPT | P43490 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | AURKA | O14965 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Diphenylsulfane SCHEMBL29092790 | 0.85 | ALDH1A1 (0.73) | ALDH1A1HSD17B10MAOAMAOBRIPK2 | |
| SCHEMBL10748587 | 0.81 | ALDH1A1 (0.48) | ALDH1A1HSD17B10RIPK2KDREGFR | |
| SCHEMBL31248553 | 0.79 | CYP3A4 (0.51) | ALDH1A1HSD17B10MAOAMAOBRIPK2 | |
| SCHEMBL2564606 | 0.78 | ALDH1A1 (0.45) | ALDH1A1HSD17B10RIPK2KDREGFR | |
| SCHEMBL4054023 | 0.78 | ALDH1A1 (0.45) | ALDH1A1HSD17B10RIPK2KDRTGFBR1 | |
| SCHEMBL927048 | 0.74 | RIPK2 (0.60) | ALDH1A1HSD17B10RIPK2KDREGFR | |
| SCHEMBL29478085 | 0.74 | RIPK2 (0.60) | ALDH1A1HSD17B10RIPK2KDREGFR | |
| Benzo[D]Thiazole SCHEMBL27764394 | 0.74 | HSD17B10 (0.73) | ALDH1A1HSD17B10RIPK2KDREGFR | |
| SCHEMBL21536796 | 0.74 | KCNH2 (0.46) | ALDH1A1HSD17B10RIPK2KDRTGFBR1 | |
| Benzo[D]Thiazole SCHEMBL2173015 | 0.72 | ALDH1A1 (0.95) | ALDH1A1HSD17B10RIPK2KDREGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5948608-A | CONTAINING CYANINE DYE | FUJI PHOTO FILM CO., LTD. (JP) | 1999-09-07 | — | — | US | disclosed |
| EP-0222970-B1 | SULPHOALKYLATION PROCESS | Agfa-Gevaert AG (DE) | 1990-10-24 | — | — | EP | disclosed |
| US-4883880-A | Process for the preparation of sulfoalkyl quaternary salts and for the production of alkane sultones | AGFA-GEVAERT AKTIENGESSELLSCHAFT (DE) | 1989-11-28 | — | — | US | disclosed |
| EP-0222970-A1 | Sulphoalkylation process | Agfa-Gevaert AG (DE) | 1987-05-27 | — | — | EP | disclosed |
| US-4539408-A | Process for the preparation of sulphoalkyl quaternary salts | AGFA-GEVAERT AKTIENGESELLSCHAFT (DE) | 1985-09-03 | — | — | US | disclosed |
| US-4504668-A | Process for the preparation of N-sulfoalkyl quaternary salts of nitrogen heterocyclics | AGFA-GEVAERT AKTIENGESELLSCHAFT (DE) | 1985-03-12 | — | — | US | disclosed |
| EP-0064667-B1 | PROCESS FOR THE PREPARATION OF SULFOALKYL QUATERNARY SALTS | Agfa-Gevaert AG (DE) | 1984-11-28 | — | — | EP | disclosed |
| EP-0055428-B1 | BIS-(3-SULFOPROPYL)ETHERS, PROCESS FOR THEIR PREPARATION AND THEIR USE AS ALKYLATING AGENTS FOR ORGANIC BASES | Agfa-Gevaert AG (DE) | 1984-03-14 | — | — | EP | disclosed |
| EP-0034279-B1 | SULFOALKYLATING AGENTS, PROCESS FOR THEIR PREPARATION AND THEIR USE IN THE MANUFACTURE OF QUANTERNARY SULFOALKYL SALTS | Agfa-Gevaert AG (DE) | 1983-06-22 | — | — | EP | disclosed |
| EP-0064667-A1 | Process for the preparation of sulfoalkyl quaternary salts | Agfa-Gevaert AG (DE) | 1982-11-17 | — | — | EP | disclosed |
| EP-0055428-A1 | Bis-(3-sulfopropyl)ethers, process for their preparation and their use as alkylating agents for organic bases | Agfa-Gevaert AG (DE) | 1982-07-07 | — | — | EP | disclosed |
| US-4308390-A | Process for the production of sulphoalkyl quaternary salts | AGFA-GEVAERT AKTIENGESELLSCHAFT (DE) | 1981-12-29 | — | — | US | disclosed |
| EP-0034279-A2 | Sulfoalkylating agents, process for their preparation and their use in the manufacture of quanternary sulfoalkyl salts | Agfa-Gevaert AG (DE) | 1981-08-26 | — | — | EP | disclosed |