Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.38 |
| ▸ | TRPM5 | Q9NZQ8 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.37 |
| ▸ | PTK6 | Q13882 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | NAMPT | P43490 | 1/20 | 0.35 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.35 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.34 |
| ▸ | RIPK2 | O43353 | 7/20 | 0.34 |
| ▸ | KDR | P35968 | 3/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4054163 | 0.85 | NPC1 (0.47) | ALDH1A1HSD17B10SMN1; SMN2KDM4ENPC1 | |
| SCHEMBL10748587 | 0.84 | ALDH1A1 (0.48) | ALDH1A1HSD17B10TRPM5MAPK1SMN1; SMN2 | |
| SCHEMBL2564606 | 0.81 | ALDH1A1 (0.45) | ALDH1A1HSD17B10TRPM5MAPK1SMN1; SMN2 | |
| SCHEMBL8471890 | 0.78 | ALDH1A1 (0.52) | ALDH1A1HSD17B10HSD11B1KDM4ENPC1 | |
| SCHEMBL21536796 | 0.77 | KCNH2 (0.46) | ALDH1A1HSD17B10TRPM5MAPK1SMN1; SMN2 | |
| SCHEMBL2594624 | 0.75 | RIPK2 (0.66) | RIPK2KDRTGFBR1 | |
| SCHEMBL8032080 | 0.74 | TYMS (0.37) | ALDH1A1HSD17B10KDM4E | |
| SCHEMBL172097 | 0.74 | ALDH1A1 (0.54) | ALDH1A1HSD17B10TRPM5MAPK1SMN1; SMN2 | |
| SCHEMBL29870586 | 0.74 | ALDH1A1 (0.54) | ALDH1A1HSD17B10TRPM5MAPK1SMN1; SMN2 | |
| SCHEMBL23478698 | 0.73 | ALDH1A1 (0.41) | ALDH1A1HSD17B10TRPM5MAPK1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240018156-A1 | SPIROCYCLIC COMPOUNDS | C4 THERAPEUTICS, INC. (US) | 2024-01-18 | — | — | US | disclosed |
| US-11623929-B2 | Spirocyclic compounds | C4 THERAPEUTICS, INC. (US) | 2023-04-11 | — | — | US | disclosed |
| EP-3892618-A1 | 4-PYRIDINYL FORMAMIDE COMPOUND OR DERIVATIVE THEREOF, PREPARATION METHOD THEREFOR, HERBICIDAL COMPOSITION AND USE THEREOF | Qingdao KingAgroot Chemical Compound Co., Ltd. (CN) | 2021-10-13 | — | — | EP | disclosed |
| US-20210070763-A1 | SPIROCYCLIC COMPOUNDS | C4 THERAPEUTICS, INC. (US) | 2021-03-11 | — | — | US | disclosed |
| US-10000500-B2 | Coelenterazine analogues | PROMEGA CORPORATION (US) | 2018-06-19 | — | — | US | disclosed |
| US-7598026-B2 | Image forming method using a silver halide color photographic light-sensitive material, and silver halide color photographic light-sensitive material | FUJIFILM CORPORATION (JP) | 2009-10-06 | — | — | US | disclosed |
| CN-101124516-A | Pattern forming material, pattern forming apparatus, and pattern forming method | FUJI FILM CORP (JP) | 2008-02-13 | — | — | CN | disclosed |
| US-20070172777-A1 | Image forming method using a silver halide color photographic light-sensitive material, and silver halide color photographic light-sensitive material | FUJI PHOTO FILM CO., LTD. | 2007-07-26 | — | — | US | disclosed |
| US-20050170299-A1 | Image forming method using a silver halide color photographic light-sensitive material, and silver halide color photographic light-sensitive material | FUJI PHOTO FILM CO., LTD. | 2005-08-04 | — | — | US | disclosed |
| US-6916601-B2 | Image-forming method using a silver halide color photographic light-sensitive material, and silver halide color photographic light-sensitive material | FUJI PHOTO FILM CO., LTD. (JP) | 2005-07-12 | — | — | US | disclosed |
| US-5491057-A | FREE FROM FLUCTUATION OF SENSITIVITY UNDER SPONTANEOUS STORAGE | FUJI PHOTO FILM CO., LTD. (JP) | 1996-02-13 | — | — | US | disclosed |
| US-5478719-A | Containing at least one compound having methine dye covalently bonded to styryl base; sensitivity, storage stability | FUJI PHOTO FILM CO., LTD. (JP) | 1995-12-26 | — | — | US | disclosed |
| US-5459025-A | Methine dye contains hydrazine group, nonfogging, improved sensitivity | FUJI PHOTO FILM CO., LTD. (JP) | 1995-10-17 | — | — | US | disclosed |
| US-5387502-A | Containing specified cyanine dye sensitizer; high sensitivity, storage stability | FUJI PHOTO FILM CO., LTD. (JP) | 1995-02-07 | — | — | US | disclosed |
| US-5356769-A | Improved storage stability | FUJI PHOTO FILM CO., LTD. (JP) | 1994-10-18 | — | — | US | disclosed |
| US-5340694-A | Containing hydrazine compound and cyanine dye; sensitivity, storage stability | FUJI PHOTO FILM CO., LTD. (JP) | 1994-08-23 | — | — | US | disclosed |
| US-5336594-A | With spectrally sensitizing dye; storage stability | FUJI PHOTO FILM CO., LTD. (JP) | 1994-08-09 | — | — | US | disclosed |
| US-5294532-A | Benzothiazole cyanine dye sensitizer | FUJI PHOTO FILM CO., LTD. (JP) | 1994-03-15 | — | — | US | disclosed |
| US-5242790-A | Photographic films with silver halide emulsions and cyanine dyes | FUJI PHOTO FILM CO., LTD. (JP) | 1993-09-07 | — | — | US | disclosed |
| EP-0554856-A1 | Silver halide photographic material | FUJI PHOTO FILM CO., LTD. (JP) | 1993-08-11 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10000500-B2 | Coelenterazine analogues | GLB1, TCF7L2, SI | ALDH1A1 3416/4885HSD17B10 2622/4885FGFR1 4495/4885 |
| US-20210070763-A1 | SPIROCYCLIC COMPOUNDS | CRBN, XIAP, RBX1 | ALDH1A1 1971/4885HSD17B10 1683/4885FGFR1 3206/4885 |
| US-20240018156-A1 | SPIROCYCLIC COMPOUNDS | CRBN, XIAP, RBX1 | ALDH1A1 1971/4885HSD17B10 1683/4885FGFR1 3206/4885 |
| US-11623929-B2 | Spirocyclic compounds | CRBN, XIAP, RBX1 | ALDH1A1 1971/4885HSD17B10 1683/4885FGFR1 3206/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.