SCHEMBL8472102

SCHEMBL8472102

CCC(NC(=O)CC(C)=O)=C(C)C(=O)O

nearest known ligand 0.36

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.36
TDP1 Q9NUW8 1/20 0.36
MAPT P10636 2/20 0.32
KDM4E B2RXH2 1/20 0.31
KDM6B O15054 1/20 0.31
KDM5C P41229 1/20 0.31
EGLN1 Q9GZT9 1/20 0.31
PHF8 Q9UPP1 1/20 0.31
KDM2A Q9Y2K7 1/20 0.31
FFAR3 O14843 1/20 0.31
THRB P10828 1/20 0.31
FNTA P49354 1/20 0.31
FNTB P49356 1/20 0.31
PGGT1B P53609 1/20 0.31
MGAM O43451 1/20 0.30
GAA P10253 1/20 0.30
SI P14410 1/20 0.30
MGAM2 Q2M2H8 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9317787 0.82 SMN1; SMN2 (0.31) ALDH1A1
SCHEMBL1011842 0.80 FFAR3 (0.35) ALDH1A1TDP1FFAR3THRBFNTA
SCHEMBL9013440 0.77 CRBN (0.42) ALDH1A1TDP1MAPTFFAR3THRB
SCHEMBL472247 0.77 CRBN (0.42) ALDH1A1TDP1MAPTFFAR3THRB
SCHEMBL2780583 0.74 ALDH1A1 (0.33) ALDH1A1GAA
SCHEMBL2780587 0.74 ALDH1A1 (0.33) ALDH1A1GAA
SCHEMBL4395851 0.73 ALDH1A1 (0.43) ALDH1A1TDP1MAPTKDM4EKDM6B
SCHEMBL844488 0.73 TDP1 (0.36) ALDH1A1TDP1FFAR3THRBFNTA
SCHEMBL844490 0.73 TDP1 (0.36) ALDH1A1TDP1FFAR3THRBFNTA
SCHEMBL11029326 0.72

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024107042-A1 SILANE COMPOUND AND COMPOSITIONS CONTAINING SAME SYNTHOMER SDN BHD (MY) 2024-05-23 WO claimed
EP-4320174-A1 POLYMER LATEX COMPOSITION Synthomer Sdn. Bhd. (MY) 2024-02-14 EP claimed
EP-4308613-A1 POLYMER LATEX COMPOSITION Synthomer Sdn. Bhd. (MY) 2024-01-24 EP claimed
WO-2022216149-A1 POLYMER LATEX COMPOSITION SYNTHOMER SDN BHD (MY) 2022-10-13 WO claimed
US-20240174784-A1 POLYMER LATEX COMPOSITION SYNTHOMER SDN. BHD. (MY) 2024-05-30 US disclosed
US-20240166784-A1 POLYMER LATEX COMPOSITION SYNTHOMER SDN. BHD. (MY) 2024-05-23 US disclosed
WO-2024107042-A1 SILANE COMPOUND AND COMPOSITIONS CONTAINING SAME SYNTHOMER SDN BHD (MY) 2024-05-23 WO disclosed
EP-4320174-A1 POLYMER LATEX COMPOSITION Synthomer Sdn. Bhd. (MY) 2024-02-14 EP disclosed
EP-4308613-A1 POLYMER LATEX COMPOSITION Synthomer Sdn. Bhd. (MY) 2024-01-24 EP disclosed
WO-2022216149-A1 POLYMER LATEX COMPOSITION SYNTHOMER SDN BHD (MY) 2022-10-13 WO disclosed
WO-2022197175-A1 POLYMER LATEX COMPOSITION SYNTHOMER SDN BHD (MY) 2022-09-22 WO disclosed
US-8809447-B2 Acetoacetate-functional monomers and their uses in coating compositions EASTMAN CHEMICAL COMPANY (US) 2014-08-19 US disclosed
US-8809446-B2 Substituted 3-oxopentanoates and their uses in coating compositions EASTMAN CHEMICAL COMPANY (US) 2014-08-19 US disclosed
EP-2651873-A1 SUBSTITUTED 3-OXOPENTANOATES AND THEIR USES IN COATING COMPOSITIONS Eastman Chemical Company (US) 2013-10-23 EP disclosed
EP-2651874-A1 ACETOACETATE-FUNCTIONAL MONOMERS AND THEIR USES IN COATING COMPOSITIONS Eastman Chemical Company (US) 2013-10-23 EP disclosed
US-20120157609-A1 SUBSTITUTED 3-OXOPENTANOATES AND THEIR USES IN COATING COMPOSITIONS EASTMAN CHEMICAL COMPANY (US) 2012-06-21 US disclosed
US-20120157610-A1 ACETOACETATE-FUNCTIONAL MONOMERS AND THEIR USES IN COATING COMPOSITIONS EASTMAN CHEMICAL COMPANY (US) 2012-06-21 US disclosed
WO-2012082340-A1 SUBSTITUTED 3-OXOPENTANOATES AND THEIR USES IN COATING COMPOSITIONS EASTMAN CHEMICAL COMPANY (US) 2012-06-21 WO disclosed
WO-2012082348-A1 ACETOACETATE-FUNCTIONAL MONOMERS AND THEIR USES IN COATING COMPOSITIONS EASTMAN CHEMICAL COMPANY (US) 2012-06-21 WO disclosed
US-5990224-A CURABLE COATINGS OBTAINED BY POLYMERIZATION OF AN UNSATURATED MONOMER HAVING AN ACETOACETOXY GROUP IN THE PRESENCE OF A PHOSPHATE-CONTAINING SURFACTANT AND POLYAMINE; GELATION INHIBITION; PROTECTIVE COATINGS AND SEALS; PAINTS, INKS, EASTMAN CHEMICAL COMPANY (US) 1999-11-23 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120157610-A1 ACETOACETATE-FUNCTIONAL MONOMERS AND THEIR USES IN COATING COMPOSITIONS ACACA, AMD1, ACAT2 ALDH1A1 17/4885TDP1 1735/4885MAPT 2463/4885
US-20120157609-A1 SUBSTITUTED 3-OXOPENTANOATES AND THEIR USES IN COATING COMPOSITIONS OXER1, C9, OXGR1 ALDH1A1 1038/4885TDP1 1032/4885MAPT 4062/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.