Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 5/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.34 |
| ▸ | SLC40A1 | Q9NP59 | 2/20 | 0.34 |
| ▸ | KDM1A | O60341 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.32 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8917762 | 0.89 | KAT6A (0.38) | HTR6ALDH1A1POLBMEN1KMT2A | |
| SCHEMBL8920824 | 0.85 | SLC40A1 (0.37) | ALDH1A1POLBSLC40A1HTT | |
| SCHEMBL8917377 | 0.84 | ALDH1A1 (0.36) | HTR6ALDH1A1KMT2A | |
| SCHEMBL8918871 | 0.82 | — | — | |
| SCHEMBL8916300 | 0.80 | MEN1 (0.39) | HTR6POLBMEN1KMT2ASLC40A1 | |
| SCHEMBL8918137 | 0.78 | SLC40A1 (0.40) | ALDH1A1TSHRPOLBMEN1KMT2A | |
| SCHEMBL8918176 | 0.74 | CCR3 (0.36) | MEN1KMT2ASLC40A1HTT | |
| SCHEMBL8917696 | 0.74 | GAA (0.39) | HTR6ALDH1A1TSHRPOLBMEN1 | |
| SCHEMBL8918039 | 0.74 | HSD17B1 (0.35) | ALDH1A1MEN1KMT2ASLC40A1KDM4E | |
| SCHEMBL8918357 | 0.73 | HPGD (0.37) | ALDH1A1POLBMEN1KMT2AHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5696143-A | ARTHRITIS THERAPY | G.D. SEARLE & CO. | 1997-12-09 | — | — | US | disclosed |