Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KAT6A | Q92794 | 1/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.35 |
| ▸ | HTR6 | P50406 | 4/20 | 0.35 |
| ▸ | SLC40A1 | Q9NP59 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 5/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.34 |
| ▸ | KDM1A | O60341 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | CRHBP | P24387 | 1/20 | 0.32 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8916155 | 0.89 | HTR6 (0.36) | PTGS2HTR6SLC40A1MEN1KMT2A | |
| SCHEMBL8916300 | 0.80 | MEN1 (0.39) | HTR6SLC40A1MEN1KMT2APOLB | |
| SCHEMBL8920824 | 0.80 | SLC40A1 (0.37) | SLC40A1POLBHTTALDH1A1GAA | |
| SCHEMBL8918176 | 0.78 | CCR3 (0.36) | SLC40A1MEN1KMT2AHTT | |
| SCHEMBL8917377 | 0.76 | ALDH1A1 (0.36) | HTR6KMT2AALDH1A1 | |
| SCHEMBL8917696 | 0.75 | GAA (0.39) | HTR6MEN1KMT2APOLBKDM4E | |
| SCHEMBL8918871 | 0.75 | — | — | |
| SCHEMBL8918039 | 0.74 | HSD17B1 (0.35) | SLC40A1MEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL8918357 | 0.74 | HPGD (0.37) | PTGS2MEN1KMT2APOLBHTT | |
| SCHEMBL8917789 | 0.74 | HTR6 (0.38) | HTR6MEN1KMT2AKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5696143-A | ARTHRITIS THERAPY | G.D. SEARLE & CO. | 1997-12-09 | — | — | US | disclosed |