Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | TP53 | P04637 | 3/20 | 0.36 |
| ▸ | CSNK2A2 | P19784 | 2/20 | 0.36 |
| ▸ | CSNK2B | P67870 | 2/20 | 0.36 |
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | APOB | P04114 | 1/20 | 0.35 |
| ▸ | MTTP | P55157 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 3/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | CETP | P11597 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8476247 | 0.79 | CSNK2A2 (0.46) | ADORA3ALDH1A1KDM4EHPGDTP53 | |
| SCHEMBL7219386 | 0.74 | MAPT (0.46) | ADORA3ALDH1A1KDM4EHPGDTP53 | |
| SCHEMBL7223445 | 0.71 | ADORA3 (0.37) | ADORA3ALDH1A1KDM4EHPGDTP53 | |
| SCHEMBL8482317 | 0.67 | KDM4E (0.36) | ADORA3ALDH1A1KDM4EHPGDTP53 | |
| SCHEMBL9682715 | 0.66 | RAPGEF4 (0.41) | ALDH1A1KDM4EHPGDMAPTLMNA | |
| SCHEMBL17355772 | 0.63 | KDM4E (0.41) | ALDH1A1KDM4EHPGDMAPTCYP1A2 | |
| SCHEMBL28530767 | 0.62 | KMT2A (0.49) | HPGDSMN1; SMN2 | |
| SCHEMBL19546119 | 0.61 | ALDH1A1 (0.42) | ALDH1A1KDM4EHPGDMAPTSMN1; SMN2 | |
| SCHEMBL10462265 | 0.60 | PTGS2 (0.49) | ALDH1A1TP53MAPTSMN1; SMN2LMNA | |
| SCHEMBL14448663 | 0.60 | ALDH1A1 (0.46) | ALDH1A1KDM4EHPGDLMNAHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5977029-A | HERBICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1999-11-02 | — | — | US | disclosed |
| EP-0879232-A1 | 3-ARYL-5-HALOGEN-PYRONE DERIVATIVES AS PEST CONTROL AGENTS | BAYER AG (DE) | 1998-11-25 | — | — | EP | disclosed |
| WO-1997016436-A1 | 3-ARYL-5-HALOGEN-PYRONE DERIVATIVES AS PEST CONTROL AGENTS | BAYER AKTIENGESELLSCHAFT (DE) | 1997-05-09 | — | — | WO | disclosed |