SCHEMBL8475709

SCHEMBL8475709

COCc1cc(C(C)(C)C)[c]c(C(C)(C)C)c1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11497145 0.79
SCHEMBL284609 0.75 HSPA5 (0.39)
SCHEMBL791992 0.73 GABRA1 (0.48)
SCHEMBL2821369 0.73 ACHE (0.39)
SCHEMBL27439090 0.73 NOS1 (0.31)
SCHEMBL3624689 0.72 PRKCE (0.37)
SCHEMBL8961299 0.71 GAA (0.33)
SCHEMBL2302750 0.70 MEN1 (0.30)
SCHEMBL301056 0.70 ALDH1A1 (0.48)
SCHEMBL8961112 0.70 HPGD (0.45)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5892051-A WEAR RESISTANCE CIBA SPECIALTY CHEMICALS CORPORATION (US) 1999-04-06 US disclosed
US-5618778-A USING AN OXYORGANIC SULFIDE COMPOUND CIBA-GEIGY CORPORATION (US) 1997-04-08 US disclosed
EP-0206998-B1 LUBRICANT COMPOSITIONS, GLUCAMIN DERIVATIVES AND COMPLEX COMPOUNDS CONTAINING THEM CIBA-GEIGY AG (CH) 1993-03-17 EP disclosed
EP-0162016-B1 ADDITIVES FOR MATERIALS CIBA-GEIGY AG (CH) 1992-06-03 EP disclosed
EP-0166696-B1 LUBRICANT ADDITIVES CIBA-GEIGY AG (CH) 1989-07-19 EP disclosed
EP-0214932-B1 LUBRICANT COMPOSITIONS AND HYDRAULIC FLUIDS COMPRISING SULFURIZED PHENOL DERIVATIVES, AND SULFURIZED PHENOL DERIVATIVES CIBA-GEIGY AG (CH) 1988-09-28 EP disclosed
US-4737300-A LUBRICANTS, STABILIZERS CIBA-GEIGY CORPORATION (US) 1988-04-12 US disclosed
EP-0233140-A1 Lubricant additives containing sulphur and nitrogen CIBA-GEIGY AG (CH) 1987-08-19 EP disclosed
EP-0166696-A2 Lubricant additives CIBA-GEIGY AG (CH) 1986-01-02 EP disclosed
EP-0162016-A2 Additives for materials CIBA-GEIGY AG (CH) 1985-11-21 EP disclosed