Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A3 | Q01959 | 7/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 5/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.41 |
| ▸ | GPR88 | Q9GZN0 | 4/20 | 0.40 |
| ▸ | DHFR | P00374 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8898490 | 0.91 | GPR88 (0.43) | SLC6A3SLC6A2SLC6A4GPR88DHFR | |
| SCHEMBL8473779 | 0.91 | SLC6A3 (0.48) | SLC6A3SLC6A2SLC6A4GPR88DHFR | |
| SCHEMBL8474902 | 0.91 | SLC6A2 (0.41) | SLC6A3SLC6A2SLC6A4GPR88LMNA | |
| SCHEMBL8474565 | 0.89 | SLC6A3 (0.42) | SLC6A3SLC6A2SLC6A4GPR88DHFR | |
| SCHEMBL8477380 | 0.88 | SLC6A3 (0.42) | SLC6A3SLC6A2SLC6A4DHFR | |
| SCHEMBL8475897 | 0.82 | NPY1R (0.38) | SLC6A3SLC6A2SLC6A4GPR88ALDH1A1 | |
| SCHEMBL8472000 | 0.82 | HTR2C (0.43) | SLC6A3SLC6A2SLC6A4GPR88ALDH1A1 | |
| SCHEMBL8477072 | 0.80 | GPR88 (0.45) | SLC6A3SLC6A2SLC6A4GPR88DHFR | |
| SCHEMBL8472627 | 0.80 | SLC6A3 (0.43) | SLC6A3SLC6A2SLC6A4GPR88DHFR | |
| SCHEMBL8477091 | 0.79 | GPR88 (0.39) | SLC6A3SLC6A2SLC6A4GPR88DHFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5891902-A | OSTEOPOROSIS | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1999-04-06 | — | — | US | disclosed |
| EP-0782989-A1 | INDOLE DERIVATIVES | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1997-07-09 | — | — | EP | disclosed |