Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 3/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.41 |
| ▸ | HTR2C | P28335 | 1/20 | 0.40 |
| ▸ | HTR2B | P41595 | 1/20 | 0.40 |
| ▸ | GPR88 | Q9GZN0 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.38 |
| ▸ | CHRNA5 | P30532 | 1/20 | 0.38 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.38 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.38 |
| ▸ | EGFR | P00533 | 2/20 | 0.37 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.37 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.37 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.37 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.37 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.37 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.37 |
| ▸ | NMT1 | P30419 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8472000 | 0.91 | HTR2C (0.43) | SLC6A2SLC6A3SLC6A4HTR2CHTR2B | |
| SCHEMBL8473779 | 0.91 | SLC6A3 (0.48) | SLC6A2SLC6A3SLC6A4GPR88LMNA | |
| SCHEMBL8475904 | 0.91 | SLC6A3 (0.41) | SLC6A2SLC6A3SLC6A4GPR88LMNA | |
| SCHEMBL8474565 | 0.89 | SLC6A3 (0.42) | SLC6A2SLC6A3SLC6A4GPR88LMNA | |
| SCHEMBL8477072 | 0.89 | GPR88 (0.45) | SLC6A2SLC6A3SLC6A4HTR2CHTR2B | |
| SCHEMBL8477380 | 0.88 | SLC6A3 (0.42) | SLC6A2SLC6A3SLC6A4 | |
| SCHEMBL8898481 | 0.87 | HTR2C (0.42) | HTR2CHTR2BGPR88L3MBTL1LMNA | |
| SCHEMBL8474898 | 0.82 | EGFR (0.40) | HTR2CHTR2BGPR88L3MBTL1LMNA | |
| SCHEMBL8898490 | 0.82 | GPR88 (0.43) | SLC6A2SLC6A3SLC6A4GPR88LMNA | |
| SCHEMBL8474450 | 0.80 | LMNA (0.47) | HTR2CHTR2BLMNAEGFRMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5891902-A | OSTEOPOROSIS | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1999-04-06 | — | — | US | disclosed |
| EP-0782989-A1 | INDOLE DERIVATIVES | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1997-07-09 | — | — | EP | disclosed |