Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 1/20 | 0.43 |
| ▸ | HTR2B | P41595 | 1/20 | 0.43 |
| ▸ | GPR88 | Q9GZN0 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.37 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.36 |
| ▸ | ACACB | O00763 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8477072 | 0.93 | GPR88 (0.45) | HTR2CHTR2BGPR88MEN1NPC1 | |
| SCHEMBL8474902 | 0.91 | SLC6A2 (0.41) | HTR2CHTR2BGPR88TP53CHRM4 | |
| SCHEMBL8898490 | 0.90 | GPR88 (0.43) | GPR88ALDH1A1SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL8898481 | 0.89 | HTR2C (0.42) | HTR2CHTR2BGPR88MEN1NPC1 | |
| SCHEMBL8472627 | 0.89 | SLC6A3 (0.43) | GPR88ALDH1A1SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL8477091 | 0.87 | GPR88 (0.39) | GPR88ALDH1A1SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL8475103 | 0.85 | SLC6A3 (0.38) | ALDH1A1SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL8474450 | 0.83 | LMNA (0.47) | HTR2CHTR2BALDH1A1ALOX15KMT2A | |
| SCHEMBL8472347 | 0.83 | SMN1; SMN2 (0.41) | HTR2CHTR2BMEN1ALDH1A1KMT2A | |
| SCHEMBL8475904 | 0.82 | SLC6A3 (0.41) | GPR88ALDH1A1SLC6A2SLC6A4SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5891902-A | OSTEOPOROSIS | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1999-04-06 | — | — | US | disclosed |
| EP-0782989-A1 | INDOLE DERIVATIVES | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1997-07-09 | — | — | EP | disclosed |