Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | PARP1 | P09874 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | TACR2 | P21452 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8472581 | 0.96 | KDM4E (0.46) | KDM4EALDH1A1SMN1; SMN2HPGDMAPK1 | |
| SCHEMBL8477583 | 0.94 | ALDH1A1 (0.46) | KDM4EALDH1A1SMN1; SMN2HPGDMAPK1 | |
| SCHEMBL8476897 | 0.94 | ALDH1A1 (0.48) | KDM4EALDH1A1SMN1; SMN2HPGDMAPK1 | |
| SCHEMBL8471992 | 0.93 | KMT2A (0.47) | KDM4EALDH1A1SMN1; SMN2HPGDMAPK1 | |
| SCHEMBL8472229 | 0.92 | KDM4E (0.55) | KDM4EALDH1A1SMN1; SMN2HPGDMAPK1 | |
| SCHEMBL8477279 | 0.91 | LMNA (0.51) | KDM4EALDH1A1SMN1; SMN2HPGDMAPK1 | |
| SCHEMBL8472213 | 0.89 | KDM4E (0.53) | KDM4EALDH1A1SMN1; SMN2HPGDMAPK1 | |
| SCHEMBL8476916 | 0.89 | KDM4E (0.43) | KDM4EALDH1A1SMN1; SMN2HPGDMAPK1 | |
| SCHEMBL8477752 | 0.89 | HPGD (0.46) | KDM4EALDH1A1SMN1; SMN2HPGDMAPK1 | |
| SCHEMBL8475932 | 0.88 | ALDH1A1 (0.52) | KDM4EALDH1A1SMN1; SMN2HPGDMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5891902-A | OSTEOPOROSIS | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1999-04-06 | — | — | US | disclosed |
| EP-0782989-A1 | INDOLE DERIVATIVES | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1997-07-09 | — | — | EP | disclosed |