Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | TACR2 | P21452 | 11/20 | 0.43 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | EGFR | P00533 | 1/20 | 0.38 |
| ▸ | HTR2C | P28335 | 1/20 | 0.38 |
| ▸ | HTR2B | P41595 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8472210 | 0.92 | KDM4E (0.43) | LMNAPOLBKDM4EALDH1A1HPGD | |
| SCHEMBL8476838 | 0.91 | KDM4E (0.40) | LMNAPOLBKDM4EALDH1A1HPGD | |
| SCHEMBL8472588 | 0.89 | ALDH1A1 (0.43) | LMNAKDM4EALDH1A1HPGDALOX15 | |
| SCHEMBL8472347 | 0.88 | SMN1; SMN2 (0.41) | LMNACHRM4POLBHTR2CHTR2B | |
| SCHEMBL8898481 | 0.88 | HTR2C (0.42) | LMNACHRM4HTR2CHTR2BKDM4E | |
| SCHEMBL8474453 | 0.86 | LMNA (0.49) | LMNAMAPTPKMTACR2POLB | |
| SCHEMBL8477072 | 0.86 | GPR88 (0.45) | CHRM4HTR2CHTR2BALDH1A1ALOX15 | |
| SCHEMBL8472000 | 0.83 | HTR2C (0.43) | CHRM4HTR2CHTR2BALDH1A1ALOX15 | |
| SCHEMBL8474454 | 0.83 | LMNA (0.53) | LMNAMAPTPKMTACR2POLB | |
| SCHEMBL8475953 | 0.81 | KDM4E (0.44) | LMNAMAPTPKMKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5891902-A | OSTEOPOROSIS | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1999-04-06 | — | — | US | disclosed |
| EP-0782989-A1 | INDOLE DERIVATIVES | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1997-07-09 | — | — | EP | disclosed |