Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 2/20 | 0.46 |
| ▸ | SRC | P12931 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | PTGER4 | P35408 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | PARP1 | P09874 | 1/20 | 0.38 |
| ▸ | HTR2C | P28335 | 1/20 | 0.37 |
| ▸ | TOP2A | P11388 | 1/20 | 0.36 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.36 |
| ▸ | WEE1 | P30291 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8475687 | 0.93 | EGFR (0.48) | EGFRSRCKDM4EALDH1A1HPGD | |
| Hydrochloric Acid SCHEMBL8473318 | 0.91 | MEN1 (0.38) | EGFRSRCKDM4EALDH1A1HPGD | |
| SCHEMBL7615354 | 0.91 | DNM1 (0.41) | EGFRSRCKDM4EALDH1A1HPGD | |
| SCHEMBL8472652 | 0.90 | KDM4E (0.47) | EGFRSRCKDM4EALDH1A1HPGD | |
| SCHEMBL8474602 | 0.89 | KDM4E (0.49) | EGFRSRCKDM4EALDH1A1HPGD | |
| SCHEMBL8477752 | 0.88 | HPGD (0.46) | KDM4EALDH1A1HPGDHSD17B10PTGER4 | |
| SCHEMBL8476050 | 0.88 | NPY5R (0.47) | EGFRSRCKDM4EALDH1A1HPGD | |
| SCHEMBL8472191 | 0.87 | TAS1R3 (0.39) | EGFRSRCKDM4EALDH1A1MAPT | |
| SCHEMBL8476075 | 0.87 | LMNA (0.46) | KDM4EALDH1A1HPGDMAPTHTT | |
| SCHEMBL8477583 | 0.87 | ALDH1A1 (0.46) | KDM4EALDH1A1HPGDHSD17B10MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5891902-A | OSTEOPOROSIS | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1999-04-06 | — | — | US | disclosed |
| EP-0782988-A1 | INDOLE DERIVATIVES | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1997-07-09 | — | — | EP | disclosed |