Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.39 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | HTT | P42858 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | USP2 | O75604 | 2/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | STAT6 | P42226 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.37 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.37 |
| ▸ | CASP3 | P42574 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8472328 | 0.94 | KCNA5 (0.40) | TAS1R3TAS1R1ALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL8583082 | 0.91 | ALDH1A1 (0.48) | ALDH1A1SMN1; SMN2LMNATSHRHTT | |
| SCHEMBL8472678 | 0.89 | RAB9A (0.40) | TAS1R3TAS1R1ALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL8476267 | 0.87 | EGFR (0.46) | ALDH1A1LMNATSHRHTTKDM4E | |
| SCHEMBL8476050 | 0.87 | NPY5R (0.47) | ALDH1A1SMN1; SMN2LMNATSHRHTT | |
| SCHEMBL8475916 | 0.85 | ALDH1A1 (0.49) | ALDH1A1SMN1; SMN2LMNATSHRHTT | |
| Hydrochloric Acid SCHEMBL8473318 | 0.83 | MEN1 (0.38) | ALDH1A1LMNATSHRHTTKDM4E | |
| SCHEMBL7615354 | 0.82 | DNM1 (0.41) | ALDH1A1KDM4EMAPTCYP1A2CYP2C9 | |
| SCHEMBL8476075 | 0.82 | LMNA (0.46) | ALDH1A1SMN1; SMN2LMNATSHRHTT | |
| SCHEMBL8472652 | 0.82 | KDM4E (0.47) | ALDH1A1LMNATSHRKDM4EUSP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5891902-A | OSTEOPOROSIS | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1999-04-06 | — | — | US | disclosed |
| EP-0782988-A1 | INDOLE DERIVATIVES | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1997-07-09 | — | — | EP | disclosed |